The success of Internet applications has led to an explosive growth in the demand for bandwidth from ISPs. Managing an IP network requires collecting and analyzing network data, such as flowlevel traffic statistics. Such analyses can typically be expressed as OLAP queries, e.g., correlated aggregate queries and data cubes. Current day OLAP tools for this task assume the availability of the data...

As a case-control study of etiology, the Pneumonia Etiology Research for Child Health (PERCH) project also provides an opportunity to assess the risk factors for severe pneumonia in hospitalized children at 7 sites. We identified relevant risk factors by literature review and iterative expert consultation. Decisions for inclusion in PERCH were based on comparability to published data, analytic ...

From 2004 to 2006, 511 raccoons collected by the United States Department of Agriculture Wildlife Services as part of a study to evaluate the effects of mesomammalian predator removal on bobwhite-quail reproduction, were examined for the presence of Gnathostoma procyonis, a nematode that parasitizes the stomach of its definitive host, the raccoon. One hundred forty-one raccoons (27.6%) containe...

Culex tritaeniorhynchus is the primary vector of Japanese encephalitis virus (JEV) throughout much of the tropical and temperate climates of Asia. Several recent papers have used ecological niche modeling programs, e.g., Maxent and GARP, to predict the distribution of disease vectors (e.g. Peterson and Shaw 2003, Moffett et al. 2007). In this on-going study, we used the Maxent program to model ...

To build large collections of medical terms from semi-structured information sources (e.g. tables, lists, etc.) and encyclopedia sites on the web. The terms are classified into the three semantic categories, Medical Problems, Medications, and Medical Tests, which were used in i2b2 challenge tasks. We developed two systems, one for Chinese and another for English terms. The two systems share the...

A recombinant metallothionein CgMT1, from the Pacific oyster Crassostrea gigas, was synthesized and used as antigen in the development of antibodies and a specific enzyme-linked immunosorbent assay (ELISA). The ELISA showed that rabbit anti-CgMT1 IgG reacted with purified CgMT1 and MTs from other marine bivalves, indicating its suitability as a reagent to quantify MTs and for monitoring of meta...

We present a neural network based method (ChloroP) for identifying chloroplast transit peptides and their cleavage sites. Using cross-validation, 88% of the sequences in our homology reduced training set were correctly classified as transit peptides or nontransit peptides. This performance level is well above that of the publicly available chloroplast localization predictor PSORT. Cleavage site...

In this paper we present a new online search engine developed in Chile: Inquiro.CL. This new search engine lets users search the Latin-American web (specifically, ten Spanishspeaking countries) by specifying their search domain (.cl, .com.ar, .com.mx, and the rest of Latin America). The structure is based on a distributed architecture that manages two document collections. The first is a cache ...

We describe a rapid, high-throughput method to scan for new RNA editing sites. This method is adapted from high-resolution melting (HRM) analysis of amplicons, a technique used in clinical research to detect mutations in genomes. The assay was validated by the discovery of six new editing sites in different chloroplast transcripts of Arabidopsis thaliana. A screen of a collection of mutants unc...

Determining the site of a regulatory phosphorylation event is often essential for elucidating specific kinase-substrate relationships, providing a handle for understanding essential signaling pathways and ultimately allowing insights into numerous disease pathologies. Despite intense research efforts to elucidate mechanisms of protein phosphorylation regulation, efficient, large-scale identific...