Meat consumption may especially increase risk of colon cancer when the meat is prepared at high temperatures and consumed by subjects with an inherited susceptibility to well-done meat. In this United States case-control study, the association between meat consumption, genetic susceptibility, and colon cancer risk was studied. Meat consumption data were available from a detailed diet history qu...

CONTEXT The necessary frequency of endoscopic colorectal cancer screening after a negative examination is uncertain. OBJECTIVE To examine the yield of adenomas and cancer in the distal colon found by repeat flexible sigmoidoscopy (FSG) 3 years after a negative examination. DESIGN, SETTING, AND PARTICIPANTS Participants were drawn from the Prostate, Lung, Colorectal, and Ovarian Cancer Scree...

Backgrounds and Objectives: Today we are witnessed a growing number of minimally invasive surgical techniques for different diseases. Laparoscopic colon surgery as a minimally invasive surgery is currently growing in treatment of malignancies after proving his place in the treatment of benign diseases. We compare in this study results of laparoscopic colorectal surgery with open surgery. Method...

Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with establishedanticancer properties. However, curcumin benefits have been impaired by its very low watersolubility, low absorption, rapid metabolism and clearance from the body. Recently,nanotechnology promises to be helpful in development of drugs delivery systems by recentadvances in macromolecular design of nanocar...

The association between colonoscopists with a low adenoma detection rate (ADR) and interval cancers led to research into different approaches to improve the quality of colonoscopy. High quality cleansing promoted the detection of neoplastic lesions, particularly the flat ones (e.g., sessile serrated polyps) with increased malignant potential, and inadequate bowel preparation increased the risk ...

Over the past few decades, surgeons have made many attempts to reduce the incidence of surgical site infections (SSI) after elective colorectal surgery. Routine faecal diversion is no longer practiced in elective colonic surgery and mechanical bowel preparation is on the verge of being eliminated altogether. Intravenous antibiotics have become the standard of care as prophylaxis against SSI for...

BACKGROUND The guidelines for colonoscopy present withdrawal time (WT) and adenoma detection rate (ADR) as the quality indicator. The purpose of this retrospective study is to analyze the predicting factors with polyp detection rate (PDR) as a surrogate for ADR by using comprehensive health checkup data, and assess the correlation between PDR per each colonic segment and WT, and factors influen...

One hundred and fifteen patients attending a gastroenterology clinic were investigated by flexible sigmoidoscopy as outpatients. There were asked to fast before the examination and give a high-volume enema and sedated before the examination. A standard long colonoscope was used rather than the 60-cm sigmoidoscope, which limits the distance that can be examined and forces the operator to work ve...

Suspensions of isolated colonic epithelial cells (colonocytes) have been obtained from rats by incubating everted lengths of colon with EDTA at 37°C in Krebs-Henseleit saline from which calcium was omitted and containing 0-25 % (w/v) bovine serum albumin. Measurements of oxygen consumption and lactate production by cell suspensions indicate that they are metabolically active for at least one ho...