BACKGROUND Studies have shown the existence of gender- and age-related differences in the incidence and anatomic distribution of colorectal cancers. The purposes of this study were to analyze the distribution characteristics of colorectal cancer patients regarding gender, age, location and tumor size in the course of colonoscopy. MATERIALS AND METHODS All colorectal cancer patients who underw...

We read with great interest the systematic review and meta-analysis by Schmid et al. on time spent sedentary and risk of cancer (1). Comparing the highest vs lowest levels of sedentary time, prolonged time spent in sedentary pursuits is associated with increased risks of colon, endometrial, and lung cancer, but not with other types of cancers, including breast cancer. This is a very important a...

Over 1,900 colorectal tumors will arise in association with a hereditary colorectal cancer syndrome in Spain in 2009. The genetic defects responsible for the most common syndromes have been discovered in recent years. Genetic testing helps diagnose affected individuals and allows identification of individuals at-risk. Colonoscopy and prophylactic colectomy decrease colorectal cancer incidence a...

synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

background of the study: colorectal cancer (crc) which is the third most diagnosed cancer throughout the world is steadily rising in the asian countries with the incidence rates mimicking the western counterparts. the pre-neoplastic nature of the transitional mucosa (tm) adjoining crc lacks conclusive evidence so far. pertaining to this, the study of the mucus layer, the functional component of...

primary colorectal lymphoma (pcl) is a rare condition that accounts for a small percentage of all gastrointestinal (gi) malignancies. there are several reports in the literature regarding the most common features of pcl. however, primary lymphoma in the rectosigmoid junction has been rarely reported. our case was a 67-year-old male who presented with non-specific symptoms of bowel obstruction w...

the aim of this study was to test the therapeutic efficacy of sodium alginate in a rat model of trinitrobenzene sulfonic acid (tnbs)-induced inflammatory bowel disease. this experiment was carried out using 77 sprague-dawley rats which were divided into six groups; normal, control, prophylactic, therapeutic and two experimental groups. rats were sacrificed 1, 2, 3 and 6 weeks after colitis indu...

Background: Routine screening colonoscopy is on the rise and pathologists have to deal with the ever larger numbers of excised colonic polyps. It is very important to optimize the patients’ individual treatment and further surveillance. Pathologists play a critical role in management, as most of the clinical decisions concerning colonic polyp managemen...