نتایج جستجو برای: combined chemoradiation
تعداد نتایج: 380860 فیلتر نتایج به سال:
We herein report a patient with advanced hepatitis B virus-related hepatocellular carcinoma (HCC) beyond the Milan criteria. He underwent orthotopic liver transplantation after successful HCC downstaging that satisfied the University of California, San Francisco criteria, using concurrent chemoradiation therapy with a combination of repeated hepatic arterial infusion chemotherapy (HAIC) and sor...
BACKGROUND AND PURPOSE In the present study, prognostic values of several CT-based pre-treatment nodal and treatment-related characteristics were evaluated among patients with squamous cell head and neck cancer treated with non-surgical modalities. PATIENTS AND METHODS Included were 79 patients with 210 pathological nodes, who underwent primary irradiation or chemoradiation. Several nodal cha...
Antiangiogenic therapy has shown clear activity and improved survival benefit for certain tumor types. However, an incomplete understanding of the mechanisms of action of antiangiogenic agents has hindered optimization and broader application of this new therapeutic modality. In particular, the impact of antiangiogenic therapy on tumor blood flow and oxygenation status (i.e., the role of vessel...
BACKGROUND Associations between anemia and outcomes of chemoradiation have been documented in several malignancies, but few data exist for limited small-cell lung cancer (LD-SCLC). This combined analysis of 652 patients in two randomized clinical trials in LD-SCLC carried out by the National Cancer Institute of Canada Clinical Trials Group was undertaken to explore the relationship between anem...
BACKGROUND Preoperative chemoradiation combined with surgery has been of focus recently in order to improve prognosis in esophageal squamous cell carcinoma (ESCC) patients. Finding biological markers that may assist in predicting the therapeutic effect of chemoradiation may benefit the treatment effect. In this study, the role of RUNX3 in the formation of cisplatin resistance in ESCC was examin...
We studied the effect of Age-Adjusted Comorbidity Index Score in colorectal cancer patients who underwent similarly aggressive treatment. Using the National Health Insurance Research Database of Taiwan, we identified 5643 patients with colorectal cancer who underwent surgical resection and chemoradiation from 2007 through 2011. We estimated survival according to Age-Adjusted Comorbidity Index S...
Randomized phase II trial of preoperative combined modality chemoradiation for distal rectal cancer.
3535 Background: Potential advantages of preoperative radiotherapy (RT) include increased resectability, sphincter preservation, local control, and overall survival. This randomized phase II study was designed to evaluate, pathologic complete response(pCR) to preoperative combined-modality chemotherapy with 5-fluorouracil (5FU) and RT, or with 5FU, irinotecan (I) and RT in patients with adenoca...
Radiation-induced sarcoma is a rare complication of radiation therapy. We report a case of radiation-induced chondrosarcoma of the maxilla. An 80-year-old Persian woman developed radiation-induced chondrosarcoma of the left maxilla 7 years after combined chemotherapy and external beam radiation therapy for the Ann Arbor stage IE malignant lymphoma of the right tonsil. She underwent suboptimal t...
Survival for patients with stage III non-small-cell lung cancer has gradually improved in recent years, with median survival times increasing from less than 10 months to more than 18 months. These increases are thought to result primarily from advances in chemoradiation. This article reviews major advances in the development of chemoradiation for patients with locally advanced non-small-cell lu...
Purpose: The combination of radiationwith chemotherapy is themost effective therapy for unresectable pancreatic cancer. To improve upon this regimen, we combined the selective Checkpoint kinase 1 (Chk1) inhibitor MK8776 with gemcitabine-based chemoradiation in preclinical pancreatic cancer models. Experimental Design: We tested the ability of MK8776 to sensitize to gemcitabine-radiation in homo...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید