Objective: Diabetes causes free radical production, oxidative stress and alterations in mitochondrial enzymes and apoptosis. The purpose of this study was to investigate the effect of aerobic exercise and consumption of L-carnitine on BCL2 and some mitochondrial enzymes of the kidney in diabetic rats. Materials and Methods: In this experimental study, 45 male wistar rats (200-300 gr) were simp...

The relative sensitivity and specificity of individual and combined noninvasive tests to detect coronary heart disease were evaluated in 75 patients with chest pain admitted for cardiac catheterization and coronary arteriography. Of the 75 patients, 56 had coronary heart disease. Exercise-induced ST-segment abnormalities (>1 mm) were found in 58%. In contrast, computer-processed exercise thalli...

Genetic factors determining exercise capacity and the magnitude of the response to exercise training are poorly understood. The aim of this study was to identify quantitative trait loci (QTL) associated with exercise training in mice. Based on marked differences in training responses in inbred NZW (-0.65 ± 1.73 min) and 129S1 (6.18 ± 3.81 min) mice, a reciprocal intercross breeding scheme was u...

OBJECTIVE Cardiovascular drift (CVdrift) is characterised by a continuous, gradual increase in heart rate (HR) after approximately 10 min of moderate-intensity aerobic exercise, despite maintenance of a constant work rate. This has important implications for trials that employ HR to monitor exercise intensity, as reducing work rate in order to keep HR constant could result in participants exerc...

BACKGROUND Both acute bouts of prior exercise (preconditioning) and antioxidant nutrients have been used in an attempt to attenuate muscle injury or oxidative stress in response to resistance exercise. However, most studies have focused on untrained participants rather than on athletes. The purpose of this work was to determine the independent and combined effects of antioxidant supplementation...