BACKGROUND The p53 transcription factor directs a transcriptional program that determines whether a cell lives or dies after DNA damage. Animal survival after extensive cellular damage often requires that lost tissue be replaced through compensatory growth or regeneration. In Drosophila, damaged imaginal disc cells can induce the proliferation of neighboring viable cells, but how this is contro...

Neonatal rats exposed to 95% oxygen (O2) for 7 days from birth had inhibited lung growth, DNA synthesis, and secondary septation. These parameters were rapidly restored by a period of recovery in air. Northern and Western blot analysis and immunohistochemistry were used to screen for the fibroblast growth factor receptor-1 (FGF-R1) and its high affinity ligand, basic fibroblast growth factor (b...

Herbivorous waterfowl populations have increasingly adapted to forage on agricultural land and triggered a parallel rise in damage crops. Winter wheat (Triticum aestivum) is the most commonly reported crop damaged northern Europe, farmers demand management actions mitigate economic impacts. Here, we apply two approaches (exclosure experiments undisturbed fields yield assessments subject scaring...

Abstract Increase in growth rate through genetic selection and improved nutrition broiler chickens has been associated with high body fat deposition. This is particularly evident under ad libitum feeding that normally practiced. Excessive deposition the of broilers a common problem for poultry producers consumers. Studies have shown feed restriction could decrease content increase protein carca...

Various growth factors and cytokines have been implicated in different forms of kidney enlargement. Vascular endothelial growth factor (VEGF) is essential for normal renal development and plays a role in diabetic glomerular enlargement. To explore a possible role for VEGF in compensatory renal changes after uninephrectomy, we examined the effect of a neutralizing VEGF-antibody (VEGF-Ab) on glom...