Introduction Coacervation as a technique for producing nanoparticles has many advantages. It involves only aqueous solvents and mild processing conditions and is therefore ideal for maintaining the stability of proteins and peptides. In this study, we examined the formulation of novel nanoparticles using chitosan (CS) in combination with sulfobutyl ether-7-β -cyclodextrin sodium (SB-CD) for del...

Metronidazole (MTZ) has extremely broad spectrum of protozoal and antimicrobial activity and is clinically effective in trichomoniasis, amoebic colitis, and giardiasis. This study was performed to formulate and evaluate the MTZ loaded microspheres by coacervation phase separation and surface deposition and coalescence methods using different polymers like Gelatin, Carbopol 934P, Polylactic Acid...

Lactoferrin (LF) and β-lactoglobulin (BLG) are among the protein pairs that exhibit heteroprotein coacervation, a unique and relatively unexamined type of liquid-liquid phase separation (LLPS). In prior work we found that LF and BLG undergo coacervation at highly constrained conditions of pH, ionic strength and protein stoichiometry. The molar stoichiometry in coacervate and supernatant is LF :...

The cashew (Anacardium occidentale) is a tropical flowering tree that generates globally over 4 million metric tons of nuts year. Although the nut most well-known product, other byproducts can produce additional value, including apples, nutshell liquid, cardanol, and gum. Over years, fair amount R&D has been done on in order to increase their value for different applications. In stimulate furth...

Adhesion underwater is a major challenge. Mussel-inspired complex coacervates functionalized with L-3,4-dihydroxyphenylalanine (L-DOPA) are proposed for adhesives through versatile chemistry of DOPA, however, simple, efficient, controllable, and nontoxic procedures to harness them still under investigation. In this study, inspired from the mussel byssus formation process, coacervate formed by s...

Self-healing technologies provide the long-term resilience of concrete structures by enabling self-diagnose and self-repair damages (aging cracks, cyclic load damages, corrosion-induced cracks). However, self-healing require special additives materials in addition to ones conventional concrete. Hence, it is often perceived have higher environmental impacts, therefore, necessary understand same....

angelica essential oil (ao), a major pharmacologically active component of angelica sinensis (oliv.) diels, possesses hemogenesis, analgesic activities and sedative effect. the application of ao in pharmaceutical systems had been limited because of its low oxidative stability. the ao-loaded gelatin-chitosan microcapsules with prevention from oxidation were developed and optimized using response...