نتایج جستجو برای: component leukocidin

تعداد نتایج: 618506  

Journal: :Antimicrobial agents and chemotherapy 2007
Ronald N Jones Angela M Nilius Bolanle K Akinlade Lalitagauri M Deshpande Gerard F Notario

A clinical trial of uncomplicated skin and skin structure infections (39 locations in 19 states) observed that community-associated or community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) represented 23% of all pathogens at baseline culture and 53% of 190 S. aureus isolates. CO-MRSA strains typically were Panton-Valentine leukocidin (PVL) positive (95%), contained staphylococca...

Journal: :Life and science 2023

Objective: This study is aimed to identify genes and pathways that are upregulated or downregulated by Staphylococcus aureus components using meta-analysis.Study Design: Meta-analysis of microarray Data.Place Duration Study: The was conducted at R.O. Perelman Department Dermatology, NYU Langone Medical Center, New York, USA, from January 2015 March 2015.Materials Methods: Public repository “GEO...

2016
Zarizal Suhaili Soo-Sum Lean Noor Muzamil Mohamad Abdul R. Abdul Rachman Mohd Nasir Mohd Desa Chew Chieng Yeo

Most of the efforts in elucidating the molecular relatedness and epidemiology of Staphylococcus aureus in Malaysia have been largely focused on methicillin-resistant S. aureus (MRSA). Therefore, here we report the draft genome sequence of the methicillin-susceptible Staphylococcus aureus (MSSA) with sequence type 1 (ST1), spa type t127 with Panton-Valentine Leukocidin (pvl) pathogenic determina...

2012
Nagarajan Abimanyu K Arunkumar M Saravanan G Sivakumar Padma Krishnan

Methods A total of 20 isolates of Staphylococcus aureus were isolated from 25 cases of breast abscess from a tertiary hospital during January 2010-October 2010. Isolation was done by culturing the pus sample drained from the abscess with 16 gauge needle. The S. aureus isolates were screened for susceptibility to various antibiotics including cefoxitin, clindamycin, fusidic acid, mupirocin, vanc...

2015
Harald Rouha Adriana Badarau Zehra C Visram Michael B Battles Bianka Prinz Zoltán Magyarics Gábor Nagy Irina Mirkina Lukas Stulik Manuel Zerbs Michaela Jägerhofer Barbara Maierhofer Astrid Teubenbacher Ivana Dolezilkova Karin Gross Srijib Banerjee Gerhild Zauner Stefan Malafa Jakub Zmajkovic Sabine Maier Robert Mabry Eric Krauland K Dane Wittrup Tillman U Gerngross Eszter Nagy

Staphylococcus aureus is a major human pathogen associated with high mortality. The emergence of antibiotic resistance and the inability of antibiotics to counteract bacterial cytotoxins involved in the pathogenesis of S. aureus call for novel therapeutic approaches, such as passive immunization with monoclonal antibodies (mAbs). The complexity of staphylococcal pathogenesis and past failures w...

2017
V. Balaji D.B. Yamuna Y.I. Francis G. Priya Doss

A total of 19 methicillin-resistant Staphylococcus aureus (MRSA) isolates were investigated for Panton-Valentine leukocidin (PVL) toxin, PVL gene sequence variation and PVL-encoding phages. Whole genome sequencing was performed for all isolates. Analysis of MRSA isolates (n = 19) confirmed that most MRSA (n = 11) were positive for the PVL gene and were multidrug resistant. ST772-MRSA-V was the ...

Journal: :The Turkish journal of pediatrics 2015
Arzu Karlı Nurşen Belet Keramettin Yanık Özlem Köken Mesut Kılıç Meltem Ceyhan Bilgici Gülnar Şensoy

Staphylococcus aureus is a common cause of musculoskeletal infections. Panton-Valentine leukocidin (PVL) is an exotoxin produced by S. aureus and is an important virulence factor. PVL-positive S. aureus infections have been associated with soft tissue infections and necrotizing pneumonia. In this case report, the clinical course of a 13-year-old boy who was admitted with right hip pain and feve...

Journal: :Journal of clinical microbiology 2010
Yi-Wei Tang Eric Himmelfarb Marcia Wills Charles W Stratton

We report the identification and characterization of three Staphylococcus aureus isolates recovered from throat and vaginal cultures, as well as from an axillary abscess, of a 17-year-old female who died of tampon-related toxic shock syndrome. The three S. aureus isolates were unrelated as determined by pulsed-field gel electrophoresis. The vaginal isolate was mecA, Panton-Valentine leukocidin,...

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