Beta-thalassemia (β-thal) is a congenital hemoglobinopathy explained by a decreased level (β+) or absence (βο) of β-globin gene expression. Microcytic hypochromic anemia and various clinical symptoms comprising severe anemia to clinically nonsymptomatic features. Treatment with an ordered blood transfusion and iron chelator agents can decrease transfusion iron overload that causes normal matura...

popular music has various functions in social intreactions. this study tries to answer the questions, “what are the roles of popular music in creating and developing social capital?” and through what mechanisms it leads to the generation of social capital?” the research method used in this study was qualitative including grounded theory strategy. the research data were collected through in-dept...

OBJECTIVE To evaluate the effect of Star Wars music (SWM) compared with endoscopist-selected popular music (PM) on quality outcomes in colonoscopy. DESIGN AND SETTING A single-centre, prospective, randomised controlled trial conducted in an endoscopy suite within a quaternary-centre gastroenterology unit, Melbourne, Australia. MAIN OUTCOME MEASURES The primary outcome measures were procedur...

OBJECTIVE To analyze the relationship between primary health care utilization and extended health insurance coverage under the Seguro Popular (SP) among Mexican indigenous people. METHODOLOGY A cross-sectional analysis was conducted using data from the Mexican National Nutrition Survey 2012 (n = 194,758). Quasi-experimental matching methods and nonlinear regression probit models were used to ...

In modern societies, cultural change seems ceaseless. The flux of fashion is especially obvious for popular music. While much has been written about the origin and evolution of pop, most claims about its history are anecdotal rather than scientific in nature. To rectify this, we investigate the US Billboard Hot 100 between 1960 and 2010. Using music information retrieval and text-mining tools, ...

Louis Lewin, better known for his popular works on poisons, wrote the first book on Side Effects of Drugs ("Nebenwirkungen der Arzneimitiel") in 1881. In the introduction to the 3rd edition (1899) he postulated: "As valuable as reports on side or after-effects of drugs per se may be, as much the practitioner may benefit from instructions as to how to avoid and treat such effects for his patient...

Background: Studies of diversification and trait evolution increasingly rely on combining molecular sequences and fossil dates to infer time-calibrated phylogenetic trees. Available calibration software provides many options for the shape of the prior probability distribution of ages at a node to be calibrated, but the question of how to assign a Bayesian prior from limited fossil data remains ...