The use of in vivo contrast-enhanced magnetic resonance (MR) imaging as a surrogate for photosensitizer (verteporfin) dosimetry in photodynamic therapy of pancreas cancer is demonstrated by correlating MR contrast uptake to ex vivo fluorescence images on excised tissue. An orthotopic pancreatic xenograft mouse model was used for the study. A strong correlation (r = 0.57) was found for bulk inte...

GAL, the Lower Saxony Research Network Design of Environments for Ageing, investigates how information and communication technology can provide for better environments for ageing. This paper describes a service oriented middleware platform for Ambient Assisted Living and its use in a number of different assistive systems developed in the GAL project: personal activity and household assistant, m...

The purpose of this study was to compare threshold-matched ears with and without suspected cochlear dead regions in terms of the speech perception benefit from high-frequency amplification. The Threshold Equalizing Noise Test (TEN) was used to assess the presence of dead regions. Speech perception was measured while participants were wearing a hearing aid fit to approximate DSL[i/o] targets. Co...

OBJECTIVE There is considerable variation in the national regulations of different countries for the release of patients from hospitals after radioiodine therapy. Individual variations make these practices, when based on the worst case scenarios, too restrictive for the majority of patients. However, there are cases in which strict rules are needed to comply with the dose limits to other indivi...

Interventional MRI (IMRI) has entered into a new stage in which computer-based techniques play an increasing role in planning, monitoring, and controlling the procedures. The use of interactive imaging, navigational image guidance techniques, and image processing methods is demonstrated in various applications. The integration of intraoperative MRI guidance and computer-assisted surgery will gr...

Simply stated, an enterprise resource planning (ERP) system identifies and plans “the...resources needed to take, make, ship and account for customer orders.” 1 To achieve these important tasks, ERP uses a variety of information technologies such as graphical user interfaces, relational databases, advanced computer languages and computer assisted software engineering tools. In essence, implemen...

Electrochemotherapy uses electroporation for enhancing chemotherapy. Electrochemotherapy can be performed using standard operating procedures with predefined electrode geometries, or using patient-specific treatment planning to predict electroporation. The latter relies on realistic computer models to provide optimal results (i.e. electric field distribution as well as electrodes' position and ...

OBJECTIVE Treatment of acetabular fractures remains one of the most challenging tasks that orthopaedic surgeons face. An accurate assessment of the injuries and preoperative planning are essential for an excellent reduction. The purpose of this study was to evaluate the feasibility, accuracy and effectiveness of performing 3D printing technology and computer-assisted virtual surgical procedures...

background: it was intended to investigate the effect of physical wedge (pw) and enhanced dynamic wedges (edw) on contralateral breast dose during primary breast irradiation in radiotherapy treatment, using high energy photon beams. materials and methods: the varian’s clinac dual mode linear accelerator model 2100 c/d and siemen’s primus accelerators were used for radiation doses with 6 mv and ...