Adolescence is a transitional stage of physical and psychological human development that generally occurs during the period from puberty to legal adulthood. There are approximately 1.2 billion adolescents (10-19 years) globally, roughly 90% of whom live in low and middle-income countries. Most are healthy, but there is still significant death, illness and diseases among adolescents. Illnesses...

the objective of this study was to determine the prevalence and incidence of venous thromboembolism among critically ill medical surgical patients. in this cross sectional and retrospective study, we observed 243 patients who were first admitted at the intensive care unit. patients who were diagnosed with deep venous thrombosis or embolism either by clinical or paraclinical methods were enrolle...

Children born with non-optimal birth characteristics - that is, are small for gestational age and/or preterm - have an increased risk for several long-term effects such as neurological sequelae and chronic disease. The purpose of this study was to examine whether twins exhibited a different outcome, compared with singletons, in terms of hospitalization during adolescence and early adulthood, an...

The discovery that thalidomide can cause human malformations has been followed in recent years by a large number of reports of malformations in the offspring of women who have taken other drugs in pregnancy. But it has remained uncertain whether any of these drugs are teratogenic, since those reporting on them have not been in a position to relate their findings to the distribution of malformat...

I N SPITE of new discoveries and advances in the treatment of rheumatoid arthritis, the most important part of the management of patients with this disease today is the prevention or minimizing of deformity and the maintenance or improvement of function. The numerous remedies that have been promoted for use in arthritis tend to detract from the appreciation of the value of physical treatment in...

In this retrospective cohort study based in Taiwan, we reported the current epidemiology of patients with multiple myeloma and analyzed the factors affecting mortality. We identified 7285 patients with newly diagnosed multiple myeloma (MM) between 1997 and 2013 in Taiwan. Privileges data from the National Health Institute Research Database was used, as it is made readily available to the public...

With the uncertainty as to the etiology and the complexities often encountered in its treatment, a pilonidal sinus has been considered as a tricky disease. Wide varieties of approaches are employed in dealing with this ailment ranging from a conservative treatment to an extensive surgical excision or repair. However, a method of simple lying open of pilonidal sinus is still considered as the fa...

Delirium is a common accompaniment of physical illness in old age, affecting approximately one out of five of those admitted to medical wards, the number being higher for elderly with fractured femurs. Although its existence has long been recognized its exact pathophysiology has not yet been fully elucidated. The present article presents up-to-date information concerning the etiology, pathophys...

This article addresses the complexity in diagnosis, gender assignment and management in patients with sexual ambiguity and malformed sexual organs. Between 1984 and 1993, nine children and 10 adult patients with this ailment were treated in the University Teaching Hospital, Lusaka, Zambia. All children had clitorovaginoplasty and adults had different surgical procedures such as feminisation and...