a retrospective study was conducted on 50 pregnancies in 41 kidney transplant recipients. 37 pregnancies were successful (74%), while in 13 cases the pregnancy was lost (7 abortions,s intra-uterine fetal deaths and one therapeutic termination). the pregnancy course was uneventful in 38 cases (76%) but in 12 there were complications, such as hypertension or slight rise in serum creatinine. pregn...

We describe a patient with multiple congenital anomalies including deafness, lacrimal duct stenosis, strabismus, bilateral cervical sinuses, congenital cardiac defects, hypoplasia of the corpus callosum, and hypoplasia of the cerebellar vermis. Mutation analysis of EYA1, SIX1, and SIX5, genes that underlie otofaciocervical and/or branchio-oto-renal syndrome, was negative. Pathologic diagnosis o...

Congenital agenesis of the inferior vena cava is an uncommon congenital anomaly which can be misdiagnosed. Agenesis of the inferior vena cava has an incidence of 0.0005% to 1% in the general population [1]. The most common cause of agenesis of the inferior vena cava is the failure of embryological development between the sixth and the tenth weeks of gestation. Heterotaxy syndrome is associated ...

Understanding how the pancreas develops is essential to understand the pathogenesis of congenital pancreatic anomalies. Recent studies have shown the advantages of investigating the development of frogs, mice, and chickens for understanding early embryonic development of the pancreas and congenital anomalies, such as choledochal cysts, anomalous pancreaticobiliary junction, annular pancreas, an...

aplasia cutis conginita (acc) is a condition characterized by congenital absence of skin, usually on the scalp. acc can occur as an isolated condition or in the presence of other congenital anomalies. here we describe a case of a 16 days old baby girl with an isolated acc of the scalp. her elder two siblings have been diagnosed with acc with concomitant cardiac or limb anomalies. the patient wa...

Congenital anomalies that are diagnosed in at least 120,000 US infants every year are the leading cause of infant death and contribute to disability and pediatric hospitalizations. Several large-scale epidemiologic studies have provided substantial evidence of an association between congenital anomalies and cancer risk in children, suggesting potential underlying cancer-predisposing conditions ...

BACKGROUND The risk of congenital anomalies in twins is higher than in singletons, but it is less well reported in relation to chorionicity. The aim of this study was to describe the prevalence of congenital anomalies in twin pregnancies by chorionicity and by major subtype and compare the rates with those in singletons. METHODS The study population included 2329 twin pregnancies (4658 twins)...