Orf virus, the prototype parapoxvirus, is responsible for contagious ecthyma in sheep and goats. The central region of the viral genome codes for proteins highly conserved among vertebrate poxviruses and which are frequently essential for viral proliferation. Analysis of the recently published genome sequence of orf virus revealed that among such essential proteins, the protein orfv075 is an or...

Viral Characteristics Large, enveloped (some virions contain double envelope), double-stranded DNA viruses (see Fig. 10.1). The capsid / nucleocapsid is brick-shaped to ovoid containing the genome and lateral bodies (function unknown). The large complex genome consists of a single, linear molecule of double stranded DNA that codes for approximately 200 proteins. The ends are ligated to each oth...

  Sheeppox virus (SPV) and goatpox virus (GPV) belong to the capripoxvirus genus of Poxviridae family. Sheeppox and goatpox along with contagious ecthyma (CE) are endemic diseases in Iran. Capripox laboratory conformation based on virological and serological techniques are time consuming, laborious and most of them of low specificity, because of close antigenic relationship between capripoxviru...

sheeppox virus (spv) and goatpox virus (gpv) belong to the capripoxvirus genus of poxviridae family. sheeppox and goatpox along with contagious ecthyma (ce) are endemic diseases in iran. capripox laboratory conformation based on virological and serological techniques are time consuming, laborious and most of them of low specificity, because of close antigenic relationship between capripoxvirus ...

Figure. Round, non-tender skin lesion on 2-year-old female buttock. Note the black ulcerated center of the lesion and its red margins. A healthy 2-year-old female presented with a round, non-tender skin lesion on her buttock, its center black and ulcerated, its margins red. It began as a small black spot a week before and subsequently enlarged and ulcerated, without blister formation, reaching ...

Bullous pemphigoid (BP) is a chronic, autoimmune, subepidermal blistering skin disease with varied clinical presentations. Diagnosis is based on the clinical picture, histopathological findings, and direct and indirect immunofluorescence studies. In unclear cases, ELISA or Western blot analysis helps to establish a definite diagnosis by the detection of immunoglobulin G autoantibodies specific ...

Ecthyma Gangrenosum is a severe skin disease commonly associated with Pseudomonas aeruginosa septicemia, there an increased risk of infection in patients malignancy undergoing chemotherapy notably Chronic lymphocytic leukemia (CLL). We present case report CLL patient infested by P. aeruginosa.