The effects of inosine (INO) on substrate metabolism and rigor formation in ischemic myocardium were examined in isolated rabbit hearts. Metabolite content was assessed in tissue extracts by chemical analysis and in the whole heart by `C and 31P nuclear magnetic resonance spectroscopy. In ischemic hearts metabolizing either [3-'3Clpyruvate or [1-13C glucose, 1 mM INO increased both total and D3...

In this minireview, the author summarized the works on rapid cooling contracture (RCC), including recent reports. RCC will be employed for studying the Ca2+ release mechanism from SR and mechanical properties during contraction.

Post-burn scar contracture associated with deep second-degree or higher burns in the joint area can lead to immobility and may cause chronic ulcers, substantially impacting patients’ quality of life. Surgical intervention is necessary, local flaps skin grafts being first option. In extreme cases, free flap transfer be required address large defects that occur after release. This study presents ...

The purpose of this study was to characterize biomechanically three different toe-walking gait patterns, artificially induced in six neurologically intact subjects and to compare them to selected cases of pathological toe-walking. The subjects, equipped with lightweight mechanical exoskeleton with elastic ropes attached to the left leg's heel on one end and on shank and thigh on the other end i...

Large joint damage often leads to inability work and disability that requires long-term treatment. The development of osteoarthritis is accompanied by changes in the muscles special rehabilitation measures are needed restore their strength, symmetry load during standing steps walking. Objective. To determine most vulnerable lower extremities conditions hip knee joints using a mathematical model...

The mechanical effects of ischemic contracture may be important in the development of irreversible cellular damage as it increases mechanical stress on sarcolemmal membranes and restricts endocardial perfusion. To assess the relative importance of these mechanical effects compared with decreased energy supply in the development of irreversible injury, the effects of inhibiting ischemic contract...

A total of 95 percent of implants are placed under the muscle. The placement of the implant in the submuscular plane allows for constant massage, decreased potential contamination of the implant through the breast ducts, and less chance of hematoma formation. This is because of the decreased vascularity of the submuscular plane as compared with the subglandular plane.' Although we cannot report...

DESCRIPTION A 28-year-old man presents 5 months after a table saw crush injury to the thumb and the index finger of the right hand. Initially, he required thumb interphalangeal joint arthrodesis and ray amputation of the index finger. Postoperatively, the patient noted scarring and gradual contracture of the first web space causing pain with movement and significant restriction in the hand func...

A woman of twenty-three had noticed for two years a gradually enlarging nodule in the medial part of the sole of the left foot. It had been intermittently tender on prolonged standing. There was no history of injury. The patient’s grandmother had two nodules in the hand. On examination there was a nodule in the plantar fascia one and three-quarter inches long and a quarter of an inch wide (Fig....