Single and multiple high-dose administrations of methamphetamine (METH) differentially decrease dopamine (DA) transporter (DAT) function, as assessed by measuring [(3)H]DA uptake into rat striatal synaptosomes prepared 1 h after treatment. Prevention of METH-induced hyperthermia attenuated the decrease in DAT activity induced by multiple injections of the stimulant. Likewise, this decrease was ...

Introduction: Glioblastoma multiforme (GBM) is a highly radioresistant cancer with low survival rate. Current therapy approaches have failed to treat GBM. The aim of this study was to assess how GBM tumors respond to combination of hyperthermia and radiotherapy. Materials and Methods:   In this study, 38 GBM patients were included. 19 patients were treated ...

The present study investigated the effects of hyperthermia on the contributions of central and peripheral factors to the development of neuromuscular fatigue. Fourteen men exercised at 60% maximal oxygen consumption on a cycle ergometer in hot (40 degrees C; hyperthermia) and thermoneutral (18 degrees C; control) environments. In hyperthermia, the core temperature increased throughout the exerc...

conclusions contrast-agent-induced nephropathic changes are more closely related to the magnitude of lipid peroxidation than protein oxidation. results compared with the control group, groups cin and n + cin had significantly higher urea and lhp levels (p < 0.05 and p < 0.001, respectively) and significantly lower cu, zn-sod activity and creatinine clearance (p < 0.05). there was no statistical...

Magnetic nanoparticles have attracted attention because of their current and potential usefulness as contrast agents for magnetic resonance imaging (MRI) or colloidal mediators for cancer magnetic hyperthermia. This review examines these in vivo applications through an understanding of the involved problems and the current and future possibilities for resolving them. A special emphasis is made ...

Glioblastoma is most common and most aggressive cancer of brain. for treatment surgery is first selection and radiation therapy then chemotherapy. The median survival of Patients with GBM is less than a year after diagnosis. Glioblastoma is basically resistant to common cancer treatments. today to improve the response of patients to treatment, a number of strategies such as the use of radiation...

conclusions body temperature changes in human poisonings are a matter in need of special attention. a literature review did not reveal any controversy over hypothermia, but poisoning cases exhibit a variety of patterns of fever and hyperthermia. if there are no limits to the diagnosis of fever and hyperthermia, all cases with a poor prognosis which fail to respond to treatment could be categori...