Seizures can give rise to enduring changes that reflect alterations in gene-expression patterns, intracellular and intercellular signaling, and ultimately network alterations that are a hallmark of epilepsy. A growing body of literature suggests that long-term changes in gene transcription associated with epilepsy are mediated via modulation of chromatin structure. One transcription factor in p...

PURPOSE This retrospective audit was to assess the effect of the New General Practitioner (GP) Contract and National Institute for Health and Care Excellence (NICE) guidelines on the care and management of people with epilepsy (PWE) during the period of observation from April 2004 to April 2009. METHOD The case notes of 540 people on anti-epilepsy drugs (AEDs) aged 16 years were reviewed in 1...

In Jordan, individuals with epilepsy commonly attend neuropsychiatric clinics. The objective of this study was to assess the psychosocial outcome of epilepsy among adolescents. The study included 101 epileptic adolescents who attended the neurology clinic at the Princess Basma Teaching Hospital in Northern Jordan and 101 non-epileptic controls. Sociodemographic characteristics and all relevant ...

BACKGROUND Epilepsy is a long-term condition that requires self-management, but currently, there is no well-evaluated epilepsy self-education or self-management intervention in the United Kingdom (UK). AIM The aim of this study was to examine the views and experiences of the first participants of the Self-Management in epILEpsy UK (SMILE UK) program to assist the development of a full trial. ...

BACKGROUND The quality of epilepsy care has often been noted to be poor and fragmentary. Most people with epilepsy are solely under the care of their general practitioner (GP). Many patients report medication side-effects and poor seizure control. Most GPs accept responsibility for epilepsy care; however, many report problems with knowledge of epilepsy and nearly all support guidance on epileps...

how to cite this article: fayyazi a, khajeh a. does electroencephalography contribute to examining children with attention deficit hyperactivity disorder? iran j child neurol. 2014 summer;8(3): 65-67. letter to editor, has not abstract. references swaiman kenneth f as, ferriero d, schor n. pediatric neurology: principles & practice. 5th ed. philadelphia: elsevier/saunders; 2012. p.622-628. sado...

Introduction Epilepsy is a common neurological disorder that can cause anywhere from a brief cessation of responsiveness to severe muscle spasms with a loss of consciousness.1 This condition is usually controlled with antiepileptic drugs (AEDs). However, approximately 20% of patients with epilepsy are resistant to therapy with first-generation AEDs.2 Topiramate (Topamax®) is a second-generation...