BACKGROUND AND OBJECTIVE Propofol is commonly used in pediatric sedation, which may cause hypotension during induction. Our goal was to determine the effect of a preinduction 20-mL/kg isotonic fluid bolus on propofol-induced hypotension, assess clinical signs of hypoperfusion during hypotension, and evaluate for age-related propofol dosing differences. METHODS This prospective, randomized, co...

BACKGROUND Breast reduction surgery is a common cosmetic surgery with a high incidence of blood loss and transfusion. In this surgery, the reduction of blood loss related to surgical manipulation and the volume of resected tissue is a target. In the present study, we compared the effects of esmolol-induced controlled hypotension on surgical visibility, surgical bleeding, and the duration of sur...

The aim of this pilot study was to examine the effect combined target-controlled anesthesia and manually controlled on incidence postoperative delirium (POD) in patients undergoing spinal surgery. All were enrolled before surgery divided into 2 groups at random: one group received sevoflurane inhalation sufentanil infusion (S-S TCI group), whereas other MCI group). Data related preoperative fac...

BACKGROUND The safety of controlled hypotension during arthroscopic shoulder procedures with the patient in the beach-chair position is controversial. Current practice for the management of intraoperative blood pressure is derived from expert opinion among anesthesiologists, but there is a paucity of clinical data validating their practice. The purpose of this study was to evaluate the effect o...

Objective: To investigate the effect of acute normovolemic hemodilution (ANH) combined with controlled hypotension (CH) on extravascular lung water and systematic oxygen metabolism for elderly patients, and to explore the clinical security of ANH + CH. Methods: 45 elderly patients undergoing elective spine and hip replacement surgery were selected and randomly divided into 3 groups (n=15 in eac...

The aim of this study was to examine the effects of posthemorrhagic hypovolemia and hypotension upon the microvascular endothelial cells and on activity of antioxidant enzymes in blood, and to investigate the influence of intravenously injected endothelin-1 in rats. The experiment was conducted on 48 rats anesthetized with ethylurethane, subjected to controlled hypotension (under 35-40 mmHg) fo...

AANA Journal  April 2017  Vol. 85, No. 2 113 Hypotension and bradycardia are common adverse effects following spinal anesthesia. Ondansetron has been studied in the attenuation of spinal anesthesia– induced hypotension (SIH) and bradycardia because of its antagonistic effect on the Bezold-Jarisch reflex. The purpose of this systematic review and meta-analysis of randomized controlled trials (...