The biological and therapeutic responses to hyperthermia, when it is envisaged as an anti-tumor treatment modality, are complex and variable. Heat delivery plays a critical role and is counteracted by more or less efficient body cooling, which is largely mediated by blood flow. In the case of magnetically mediated modality, the delivery of the magnetic particles, most often superparamagnetic ir...

At the surface of iron oxide nanoparticles, an oxidized or disordered layer is often found. Due to large surface-to-volume ratio nanomaterials, such a plays important role in overall magnetic properties particles. Consequently, it characterize if applications e.g., for hyperthermia, particle imaging, ferrofluidics, are envisaged. In this work, we tuned phase 14 nm nanoparticles via annealing pr...

Abstract Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are widely used in various areas of the biomedical field: for diagnosis (Magnetic Resonance Imaging), therapeutic applications (hyperthermia, nanovectorization). These require a good stability water and no aggregation SPIONs, with well-controlled physicochemical magnetic properties. In this work, SPIONs functionalized by citrate ligan...

The magnetic properties of spinel nanoparticles are determined by crystal chemistry issues such as cation distribution and oxidation states. The cation distribution and oxidation state of Mn-Fe spinel nanoparticles have been systematically studied at various temperatures by using neutron diffraction and electron energy loss spectroscopy, respectively. The Mn-Fe spinel nanoparticles prepared by ...

The proteasome inhibitor bortezomib (BZ) has shown promising results in some types of cancer, but in others it has had minimal activity. Recent studies have reported enhanced efficacy of BZ when combined with hyperthermia. However, the use of magnetic nanoparticles to induce hyperthermia in combination with BZ has not been reported. This novel hyperthermia modality has shown better potentiation...

Magneto-plasmonic Ag/Ni and Ag/Fe nanoparticles (NPs) were synthesized in this work using the environmentally safe contaminant-free dual-pulsed Q-switched Nd:YAG 1064 nm laser ablation method. The optical magnetic characteristics of nanomaterials investigated a vibrating sample magnetometer an ultraviolet-visible absorption spectrometer. According to transmission electron microscopy (TEM), shap...

Thermoresponsive polymer-coated magnetic nanoparticles loaded with anti-cancer drugs are of considerable interest for novel multi-modal cancer therapies. Such nanoparticles can be used for magnetic drug targeting followed by simultaneous hyperthermia and drug release. Gamma-Fe(2)O(3) iron oxide magnetic nanoparticles (MNP) with average sizes of 14, 19 and 43 nm were synthesized by high temperat...

Background: Nanomaterials are extensively used from household applications to industrial applications. Nanomaterials are the substances that are synthesized in the size ranging from 1-100 nm which exhibits excellent physical and chemical properties compared to their bulk forms. Iron oxide nanoparticles (magnetic) have unique properties that make them applicable in drug delivery applications. Ho...

Adv. Mater. 2009, 21, 1–4 2009 WILEY-VCH Verlag Gmb Although many research programs focus on surfacefunctionalized quantum dots (QDs) as clinical tools to improve medical diagnosis, the primary objective of these investigations has been imaging and only a limited number of studies have explored other functionalities, including therapeutic treatment using hyperthermia. The main purpose of this w...