conclusions the effect of coadministration of nac and coq10 was neither additive nor synergic in protecting against nihl. results the temporary hearing changes that occurred 1-day post exposure were not significantly different in all groups (p > 0.05). the total recovery (between 1 - 21 days after noise exposure) varied by a frequency increase between 1.08 - 19.10 in the noise group compared to...

Background: We assessed the potential efficacy of Coenzyme Q10 (CoQ10) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). Methods: Seventy STEMI who presented ≤12 hours after onset symptoms and were scheduled for PPCI randomly assigned to standard treatments plus CoQ10 or placebo. In group, CoQ10, as an oral capsule ...

BACKGROUND Statin drugs (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) reduce the level of cholesterol by inhibiting the synthesis of mevalonate, an intermediary in the cholesterol biosynthetic pathway. Use of statin drugs has been associated with a variety of skeletal muscle-related complaints. Coenzyme Q10 (CoQ10), a component of the mitochondrial respiratory chain, is also synt...

OBJECTIVE To examine the effects of Rhodobacter sphaeroides (R. sphaeroides) supplementation as a direct-fed microbial (DFM) on rumen fermentation in dairy cows and on coenzyme Q10 (CoQ10) transition into milk, an in vitro rumen simulation batch culture and an in vivo dairy cow experiment were conducted. METHODS The characteristics of in vitro ruminal fermentation were investigated using rume...

The aim of this study was to investigate whether magnesium ascorbyl phosphate (MAP) and coenzyme Q10 (CoQ10) can protect keratinocytes against ultraviolet (UV)A irradiation by increasing the levels of glutathione (GSH). The cell survival fraction was 89.9% when the keratinocytes were irradiated with UVA at a dose of 4 J/cm2. The cell survival fractions were 48.4, 9.1 and 4.8%, at doses of 8, 16...

Maulik, Nilanjana, Tetsuya Yoshida, Richard M. Engelman, Debasis Bagchi, Hajime Otani, and Dipak K. Das. Dietary coenzyme Q10 supplement renders swine hearts resistant to ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 278: H1084–H1090, 2000.—To examine whether nutritional supplementation of coenzyme Q10 (CoQ10) can reduce myocardial ischemia-reperfusion injury, a group of swine wa...

A total of 109 patients with symptomatic essential hypertension presenting to a private cardiology practice were observed after the addition of CoQ10 (average dose, 225 mg/day by mouth) to their existing antihypertensive drug regimen. In 80 per cent of patients, the diagnosis of essential hypertension was established for a year or more prior to starting CoQ10 (average 9.2 years). Only one patie...

Although coenzyme Q10 (CoQ10) serves as an antioxidant and energy source for spermatozoa when added to stallion semen before cooling or freezing, the effects of feeding CoQ10 on quality have not been studied. We assessed daily oral ingestion CoQ10-ubiquinol by stallions their plasma concentrations quality. Seven mature Andalusian ate 1g ubiquinol/day 4 weeks followed a 4-week washout period. Fo...

Background: Polycystic ovary syndrome (PCOS) is the largest single cause of anovulatory infertility. PCOS associated with oxidative stress. Coenzyme q10 (Coq10) an antioxidant that protects mitochondria from damage caused by either insulin resistance or free radicals. The objective study was to compare effect combined Coq10 and letrozole than alone for ovulation induction in women PCOS.Methods:...

background: fatigue is a common side effect in cancer patients undergoing radiation therapy (rt). radiation-induced fatigue affects the quality of life, but there is no definitive treatment option. in this study, the weight-loaded forced swim test was performed to assess the effect of coenzyme q10 (coq10) on radiation-induced fatigue. materials and methods: a total of 60 rats were divided rando...