OBJECTIVE The aim was to report three cases of severe bilateral epithelial edema (central corneal clouding [CCC]) in association with ClearKone SynergEyes hybrid contact lenses for the vision rehabilitation of keratoconus. METHODS Retrospective case series of six eyes of three patients that developed CCC with ClearKone SynergEyes hybrid contact lens wear shortly after beginning to wear those ...

Dear Editor, Hallermann-Streiff Syndrome (HSS) is a rare genetic condition with multiple systemic involvement chiefly affecting the head and face and includes seven basic signs: dyscephalia and bird-like face, proportionate dwarfism, dental anomalies, atrophy of skin (especially on the nose), hypotrichosis, microphthalmia and congenital cataracts [1,2]. The Brown-McLean Syndrome (BMLS) is a cli...

PURPOSE To investigate the changes in Goldmann applanation tonometry (GAT) and Ocular Response Analyzer (ORA) measurements with corneal edema induced by contact lenses. METHODS Twenty-five healthy, normal subjects (age, 23 ± 2 years) had central corneal radius (CCR), ORA, GAT, and central corneal thickness (CCT) measurements performed in both eyes before a thick, soft hydrogel contact lens wa...

To the Editor: We read with great interest the article “LASIK Interface Complications: Etiology, Management, and Outcomes” by Randleman and Shah.1 We agree completely with the authors when they stated: “Clarifying the nomenclature used for each entity is critical to enhancing future communication.” It is especially important in the most rare conditions, including the one they called “pressurein...

The stroma of the human cornea has a slow tissue turnover rate and absorbs a large part of the ultraviolet light entering the eye. Also, the high demands of the eye’s optical system call for a very exact tissue organization in the corneal stroma. As a consequence, the cornea is potentially vulnerable to oxidative stress. The cytosolic copper-zinc superoxide dismutase (SOD1) [1] and the extracel...

Purpose: To study the clinical profile of patients snake venom ophthalmia presenting to tertiary health care centre. Methods: This was a prospective observational that involved25 with complaining pain, diminution vision, photophobia, conjunctival congestion , chemosis, corneal edema, erosions and anterior chamber reaction. Results: There were 18 males 7 females age group taken 30 75 years. Most...

PURPOSE To evaluate the performance of reconstructed tissue-engineered human corneal endothelium (TE-HCE) by corneal transplantation in cat models. METHODS TE-HCE reconstruction was performed by culturing 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI)-labeled monoclonal HCE cells on denuded amniotic membranes (dAMs) in 20% fetal bovine serum-containing Dulbecco's Mod...

PURPOSE To investigate the efficacy of topical applied aloe vera (AV) and to facilitate the repair of the standardized alkaline corneal ulcer in normal and diabetic rats. MATERIALS AND METHODS The corneal alkali-burn injury model was established unilaterally in Wistar rats by filter paper saturated with 0.01 M NaOH contacting the eyes for 45 seconds. Rats were divided into four groups: normal...