Single-step immunoassays that can be performed directly in solution are ideally suited for point-of-care diagnostics. Our group recently developed a new platform of bioluminescent sensor proteins (LUMABS; LUMinescent AntiBody Sensor) that allow antibody detection in blood plasma. Thus far, LUMABS has been limited to the detection of antibodies recognizing natural peptide epitopes. Here, we repo...

attributable to the use of a particle-enhanced nephelometric immunoassay (14 ) in the present study in contrast to previous studies (11, 12, 16) using a particle-enhanced turbidimetric immunoassay (10 ). Method calibration is not yet established internationally but is required to allow direct comparison between methods (18 ). In children .1 year, serum creatinine increases with age until adulth...

the determination of formation constants of binary inner transition metal complexes where m=y(iii) or la(iii) or ce(iii) or pr(iii) or nd(iii) or sm (iii) or gd (iii) or dy (iii) or th(iv) andl = creatinine have been carried out using irving–rossotti titration technique in aqueous mediaat different temperatures and at ionic strength. to understand more about the nature ofequilibrium involving i...

objective: to determine the value of random urinary protein to creatinine ratio (upcr) for diagnosis of proteinuria in pregnant women with preeclampsia. preeclampsia is the most common complication of pregnancy and one of the main causes of maternal mortality. so, early diagnosis of preeclampsia is very important. materials and methods: in this cross-sectional study 66 pregnant women suspected ...

;25% false negatives. By contrast, plasma cystatin C better reflected GFR with the strongest correlation with Cr-labeled EDTA clearance and no false negatives. In a group of adult transplant recipients at steady-state renal function (average time since transplantation, 6 years), cystatin C was shown to have a better diagnostic value than serum creatinine for a GFR cutoff set at 60 mL/min (3 ). ...

Background. Biomarkers to distinguish latent from active Mycobacterium (M.) tuberculosis infection in clinical practice are lacking. The urinary neopterin/creatinine ratio can quantify the systemic interferon-gamma effect in patients with M. tuberculosis infection. Methods. In a prospective observational study, urinary neopterin levels were measured by enzyme linked immunosorbent assay in patie...