The continuing shortage of kidneys for transplantation requires major efforts to expand the donor pool. Donation after cardiac death (DCD) increases the number of available kidneys, but it is unknown whether patients who receive a DCD kidney live longer than patients who remain on dialysis and wait for a conventional kidney from a brain-dead donor (DBD). This observational cohort study included...

Background: Pre-donation donor screening is a crucial step in ensuring the safety of both blood donors and recipients. Donors who do not meet predetermined criteria are temporarily or permanently deferred. Aim: To assess patterns prevalence deferrals at our institution. Study design: Prospective study Place duration study: Karachi Tertiary Care Hospital, from 1st January 2014 to 31st December 2...

The use of extended criteria donors is an effective way of reducing the shortage of deceased donor organs. Evidence of significant liver trauma in a deceased donor usually rules out transplantation of the liver. The aim of this study was to evaluate the use and outcomes of donor livers with preprocurement trauma. Records of all 312 deceased donors with a history of trauma between January 1986 a...

BACKGROUND Most offered pancreases are not transplanted. This study investigates the factors that inform and influence the transplant surgeon's decision to select an offered pancreas. METHODS Semi-standardized interviews were conducted with 14 highly qualified transplant surgeons from all 14 German transplant centers performing > 5 pancreas transplantations per year. The interviews focused on...

In 2003, Krieger et al. from our group published a manuscript which investigated the use of pancreas grafts for transplantation in different UNOS regions in the United States (1). It was reported that the utilization of pancreata showed a wide variation depending on the region. To approach some degree of standardization, we calculated the ratio of pancreata used for transplantation with the num...

OBJECTIVE Due to organ shortage, average waiting time for a kidney in Germany is about 4 years after start of dialysis. Number of kidney grafts recovered can only be maintained by accepting older and expanded criteria donors. The aim of this study was to analyse the impact of donor and recipient risk on kidney long-term function. METHODS All deceased kidney transplantations were considered. W...

Liver, pancreas, and kidney allografts preserved in histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions have similar clinical outcomes. This study compares HTK and UW in a large number of standard criteria donor (SCD) and extended criteria donor (ECD) livers at a single center over 5 years. All adult, cadaveric liver and liver-kidney transplants performed between...