Absolute pitch, the ability to identify or produce the pitch of a sound without a reference point, has a critical period, i.e., it can only be acquired early in life. However, research has shown that histone-deacetylase inhibitors (HDAC inhibitors) enable adult mice to establish perceptual preferences that are otherwise impossible to acquire after youth. In humans, we found that adult men who t...

Amblyopia has been conventionally defined as “a unilateral or bilateral decrease of visual acuity (VA) caused by pattern deprivation or abnormal binocular interaction, for which no cause could be detected by the physical examination of the eye and which, in some cases, could be reversed by therapeutic measures”. Recent understanding emphasizes that, amblyopia could be redefined as a syndrome, “...

A critical period for language learning is often defined as a sharp decline in learning outcomes with age. This study examines the relevance of the critical period for English-speaking proficiency among immigrants in the USA. It uses microdata from the 2000 US Census, a model of language acquisition and a flexible specification of an estimating equation based on 64 age-at-migration dichotomous ...

In contrast to the prenatal development of the cerebral cortex, when cell production, migration, and layer formation dominate, development after birth involves more subtle processes, such as activity-dependent plasticity that includes refinement of synaptic connectivity by its stabilization and elimination. In the present study, we use RNA-seq with high spatial resolution to examine differentia...

The Critical Period Hypothesis is still controversial recently, so it cannot be said to absolutely confirmed false. It more important realize the significance of application. Although exact properties this phenomenon remain unclear and literature divided, Chinese mothers choose teach English or other languages as a second language their children from very early age (0-3 years old). This paper d...