We present an analysis of crossover interference over the entire human genome, on the basis of genotype data from more than 8,000 polymorphisms in eight CEPH families. Overwhelming evidence was found for strong positive crossover interference, with average strength lying between the levels of interference implied by the Kosambi and Carter-Falconer map functions. Five mathematical models of inte...

The multi-parental Unimodal Normal Distribution Crossover (UNDX-m) that was proposed by Ono et al. and extended by Kita et al for realcoded Genetic Algorithms (GA). shows an excellent performance in optimization problems of highly epistatic fitness functions in continuous search spaces. The UNDX-m is a crossover operator that preserves the statistics such as the mean vector and the covariance m...

The viscosity of glass formers increases by several orders of magnitude upon cooling near the glass transition temperature. For strong glass formers, this increase is Arrhenius-like, that is, the viscosity increases exponentially with inverse temperature, whereas, for fragile glass formers, this increase is super-Arrhenius-like. Recent experimental and theoretical evidence indicates that fragil...

The adaptive responses of crop genotypes and patterns of genotype x location (G x L) interaction are important to crop improvement as they are the basis for selection for specific adaptation and for elucidation of the causes of G x L interaction. Their legitimate assessment, however, requires yield data for the test genotypes for a large number of sites and over multiple years. Such data are se...

Abstract In the present work, numerical simulations based on a new algorithm specific for 2D configurational topology of spin crossover nanoparticles embedded in matrix are presented and discussed framework Ising-like model taking into account short- (J) long-range (G) interactions as surface effects (L). The is applied to calculate density states each macro-state, which then used exactly therm...

We have considered the BCS-BEC crossover at T = 0 in the framework of a lattice fermion model (the extended Hubbard model). We have analyzed the case of on-site hard core repulsion (U = ∞) and intersite attraction (W < 0) in a 3D system with extended s-wave pairing symmetry. The mechanisms of density-driven and attraction-strength-driven crossover have been analyzed. We have obtained the ground...

To realize the integration of process planning and scheduling (IPPS) in the manufacturing system, a particle swarm optimization (PSO) algorithm is utilized. Based on the general PSO (GPSO) model, one GPSO algorithm is projected to solve IPPS. In GPSO, crossover and mutation operations of genetic algorithm are respectively used for particles to exchange information and search randomly, and tabu ...

Low pulling forces applied locally to cell surface membranes produce viscoelastic cell surface protrusions. As the force increases, the membrane can locally separate from the cytoskeleton and a tether forms. Tethers can grow to great lengths exceeding the cell diameter. The protrusion-to-tether transition is known as the crossover. Here we propose a unified approach to protrusions and tethers p...