The concentration of C-reactive protein (CRP) in sera from 70 patients with systemic lupus erythematosus (SLE) showed no correlation with commonly accepted laboratory indices of disease activity. Most patients had detectable serum CRP, but in some patients CRP was not found despite repeated testing. This absence of a CRP response did not appear to be related to medication. In some patients high...

abstract background and objective: c- reactive protein (crp), as an acute phase reactant and a reliable marker of inflammation, increases due to inflammatory diseases such as rheumatoid arteritis and infectious conditions. new evidence shows that vitamin d may have important effects on adjusting and reducing the immune responses. the aim of this study was to evaluate the association between ser...

C-reactive protein, CRP, is a predominant pattern-recognition receptor (PRR) in the plasma of the horseshoe crab, which recognizes lipopolysaccharide (LPS). Native CRP2 has previously been shown to exhibit agglutination activity against the polysialic capsule of Escherichia coli K1 but its role in bacterial clearance is not well characterized. In this work, the antimicrobial activity of a recom...

Increased plasma levels of both leptin and C reactive protein (CRP) have been reported in a number of conditions, including obesity, and have been linked to cardiovascular pathophysiological processes and increased cardiovascular risk; interestingly these two biomarkers appear to be able to reciprocally regulate their bioavailability, through complex mechanisms that have not been completely cla...

High sensitivity serum C-reactive protein (hs-CRP) has come into clinical use as a marker of risk for cardiovascular disease (CVD). In addition to a role as a marker of disease, CRP has also been implicated in the pathogenesis of CVD. Specific small-molecule inhibitors of CRP have recently been developed with the intent of mitigating cardiac damage during acute myocardial infarction. However, t...

OBJECTIVES Overt hypothyroidism (OH) is associated with premature atherosclerosis and coronary heart disease (CHD). Recently, C-reactive protein (CRP) and total homocysteine (tHct) emerged as additional independent cardiovascular risk factors. Subclinical hypothyroidism (SH), affecting as many as 15% of middle-aged women is not known to be associated with risk for CHD. DESIGN AND MEASUREMENTS...

C-REACTIVE PROTEIN, HOMOCYSTEINE, AND COGNITIVEPERFORMANCE IN HEALTHY ADULTSbyCHERYL L. DAHLEMay 2010Advisor: Dr. Naftali RazMajor: PsychologyDegree: Doctor of Philosophy Elevated blood levels of C-reactive protein (CRP) and homocysteine (Hcy) havereceived a great deal of attention as biomarkers for the development of cardiovascular disease. Their utility in ...