Cryptococcosis is a deadly opportunistic infection caused by an encapsulated yeast, Cryptococcocus neoformans. The major predisposing factor is the profound cellular immune defect caused by HIV infection. Despite major advances in the treatment of HIV infection with HAART, cryptococcosis is still diagnosed in Western countries, especially in patients who have limited acess to health care [1, 2]...

Background Cryptococcosis is one of the major causes mortality among HIV patients worldwide. Though most often associated with late stage infection/AIDS, a significant number cases occur in other immunocompromised such as solid organ transplant recipients and hematological malignancies. Immunocompromised are heterogeneous group their increases constantly. Since little known about incidence clin...

Cryptococcosis is the third most common invasive fungal infection in solid organ transplant recipients. The clinical approach and prognosis have already been studied this context, but results for kidney patients not specifically addressed. We performed a retrospective case-control study of adult diagnosed with cryptococcosis after transplantation between 2002 2018 France participation 30 center...

Four cases of pulmonary cryptococcosis were diagnosed by cytological detection of Cryptococcus neoformans in bronchial lavage. Three patients had underlying diseases, but not HIV infection. The chest X-rays showed 2 patients with nodular lesions and 2 with cavitary lesions. The cryptococcal antigen in the serum was positive in all four patients. In the cytology of bronchial lavage, Cryptococcus...

We report a 74-year-old woman with cervical cancer who developed pulmonary cryptococcosis which presented as a solitary focal ground-glass opacity (GGO) on high-resolution computed tomography (HRCT). Serial HRCT showed the progression from the GGO to a discrete solid nodule. We hypothesize that the initial GGO may correspond pathologically to partial filling of air spaces with cryptococcal orga...

Currently, AIDS represents the most common risk factor for the development of cryptococcosis. Despite of rapid scale-up of antiretroviral therapy programs and global investement in HIV care over the past decade, the decline in incidende and mortality rates associated with cryptococcosis has not been commensurate. This article puts into context recent diagnostics studies and morphologies with sp...

CT scans of 35 patients with intracranial cryptococcal infection were reviewed retrospectively. Studies were normal in 43% of the patients. Positive findings in others included diffuse atrophy in 34%, mass lesions (cryptococcoma) in 11%, hydrocephalus in 9%, and diffuse cerebral edema in 3%. Two unusual types of cryptococcoma were encountered, namely gelatinous pseudocysts and an intraventricul...

Sarcoidosis is a multisystem noncaseating granulomatous disease with a propensity for lung, eye, and skin which recently have been proposed that mycobacterium tuberculosis may contribute in its pathogenesis, and rarely involves central nervous system (CNS). Despite CD4+ lymphocytopenia, sarcoidosis by itself does not increase risk of opportunistic infections other than cryptococcosis. Nonethele...

Deaths caused by systemic mycoses such as paracoccidioidomycosis, cryptococcosis, histoplasmosis, candidiasis, aspergillosis, coccidioidomycosis and zygomycosis amounted to 3,583 between 1996-2006 in Brazil. When analysed as the underlying cause of death, paracoccidioidomycosis represented the most important cause of deaths among systemic mycoses (approximately 51.2%). When considering AIDS as ...