BACKGROUND Evaluating the influence of climate variability on enteric disease incidence may improve our ability to predict how climate change may affect these diseases. OBJECTIVES To examine the associations between regional climate variability and enteric disease incidence in New Zealand. METHODS Associations between monthly climate and enteric diseases (campylobacteriosis, salmonellosis, ...

Introduction Since Cryptosporidium can be transmitted by ingestion of infected food animals and poorly treated water and by direct contact1 it is possible for infection to occur through ingestion of under cooked frogs and through handling and processing of infected frogs. In Burkina Faso frogs caught are sold to market-women who treat the frogs by emptying their bowels and frying in oil before ...

Clofazimine, a lipophilic (log P = 7.66) riminophenazine antibiotic approved by the US Food and Drug Administration (FDA) with a good safety record, was recently identified as a lead hit for cryptosporidiosis through a high-throughput phenotypic screen. Cryptosporidiosis requires fast-acting treatment as it leads to severe symptoms which, if untreated, result in morbidity for infants and small ...

BACKGROUND In the winter and spring of 2011 a large outbreak of cryptosporidiosis occurred in Skellefteå municipality, Sweden. This study summarizes the outbreak investigation in terms of outbreak size, duration, clinical characteristics, possible source(s) and the potential for earlier detection using calls to a health advice line. METHODS The investigation included two epidemiological quest...

Cryptosporidiosis, microsporidiosis, and cyclosporiasis were studied in four groups of Tanzanian inpatients: adults with AIDS-associated diarrhea, children with chronic diarrhea (of whom 23 of 59 were positive [+] for human immunodeficiency virus [HIV]), children with acute diarrhea (of whom 15 of 55 were HIV+), and HIV control children without diarrhea. Cryptosporidium was identified in specim...

In developing countries, cryptosporidiosis causes moderate-to-severe diarrhea and kills thousands of infants and toddlers annually. Drinking and recreational water contaminated with Cryptosporidium spp. oocysts has led to waterborne outbreaks in developed countries. A competent immune system is necessary to clear this parasitic infection. A better understanding of the immune responses required ...

Cryptosporidium parvum is the most frequent parasitic agent that causes diarrhoea in AIDS patients in Thailand. Cryptosporidiosis outbreaks in humans may be attributed to contamination of their drinking water from infected dairy pastures. A 23-kDa glycoprotein of C. parvum (CpP23) is a sporozoite surface protein that is geographically conserved among C. parvum isolates. This glycoprotein is a p...

Despite the fact that Cryptosporidium was identified 1100 years ago, the first human cases were only reported in 1976, and only a handful of cases were diagnosed before the discovery in 1982 of Cryptosporidium as a major cause of diarrhea in patients with AIDS [1]. During the next 5 years, Cryptosporidium was recognized as an important cause of waterborne episodes of diarrhea, childhood diarrhe...

The purpose of the study was to determine if immunization with a recombinant protein (rC7) of Cryptosporidium parvum would induce immune bovine colostrum that protected calves against cryptosporidiosis following oral challenge with C. parvum oocysts. Late gestation Holstein cows with low titers of antibody to the p23 antigen of C. parvum were immunized three times with 300 microg affinity purif...

BACKGROUND Cryptosporidium is an intracellular protozoan organism which causes diarrhea, both in immunocompetent and immunocompromised hosts. Renal transplant recipients are prone to develop a variety of infections including protozoal infections. OBJECTIVES The aim of this study was to determine the prevalence of cryptosporidiosis in our renal transplant recipients presenting with acute diarr...