The prognostic relevance of BCR-ABL1 transcript type, Sokal score and smoke as synergestic factor with complete cytogenetic response in CML patients treated different TKI modalities

Background & Aims: Induced pluripotent stem cells (iPSCs) have the capability to undergo unlimited selfrenewal and differentiation into all cell types in the body. These cells are artificially derived from a nonpluripotent cell, typically human dermal fibroblasts (HDFs). The study of cytogenetic stability of these cells, in order to use iPS cells and apply studies in therapeutic applications, i...

phytoremediation of heavy metals is employed as a technological approach for a non-destructive remediation of contaminated soils. one of the most recently studied tree species used in phytoremediation applications are poplars. in this study, the one-year old rooted seedlings of populus nigra l. used to decontaminate hexavalent chromium-contaminated soils. five treatments of cr (vi) supply (were...

introduction: a comparision of cytogenetic methods in the evaluation of occupationally received radiation dose by medical radiation workwrs and a study of adaptive response to subsequent higher radiation exposure in this group.the purpose of this research was to study the effects of two cryoprotectants on viability, motility, morphology and fertilization rate of mouse sperm after freezing-thawi...

Aquatic ecosystems are facing a growing number of human induced changes and threats. Macroinvertebrate biomonitoring is particularly efficient in pinpointing the cause-effect structure between slow and subtle changes and their detrimental consequences in aquatic ecosystems. The greatest obstacle to implementing efficient biomonitoring is currently the cost-intensity of human expert taxonomic id...

The use of aquatic macroinvertebrates as bio-indicators in water quality studies has increased considerably over the last decade in Costa Rica, and standard biomonitoring methods have now been formulated at the national level. Nevertheless, questions remain about the effectiveness of different methods of sampling freshwater benthic assemblages, and how sampling intensity may influence biomonito...