Background: Low-grade oncocytic tumour (LOT) is an emerging entity describing a slow growing with morphologic features overlapping between chromophobe renal cell carcinoma (ChRCC) and oncocytoma, staining positive for cytokeratin-7 negative CD117 (c-kit). This has been recently recognised in the WHO classification of tumours 5th edition 2022. Presentation: In this case report, we present 77-yea...

Cytokeratin (pan) and epithelial membrane antigen (EMA) were considered as commonly useful epithelial markers to distinguish cancer from lymphoma, but the expression of cytokeratin (pan) and EMA had also been seen in some lymphomas. Here, we presented an unusual case of anaplastic large cell lymphoma (ALCL) absence of some lymphoid markers (Including CD3, CD20, Pax-5, CD45Ro) and positive for c...

Verruciform xanthoma is a rare tumor-like lesion, predominantly affecting the oral mucosa. Although several studies of verruciform xanthoma have been reported, the characteristic features and pathogenesis have not been fully clarified. The purpose of the present study is to perform immunohistochemical analysis using markers of proliferative cell activity and cytokeratins, and to perform compara...

PURPOSE Nodal micrometastasis and circulating tumor cells detected by multimarker quantitative real-time reverse transcription-PCR (qRT-PCR) may have prognostic importance in patients with colorectal cancer. EXPERIMENTAL DESIGN Paraffin-embedded sentinel lymph nodes from 67 patients and blood from 34 of these patients were evaluated in a prospective multicenter trial of sentinel lymph node ma...

Pancreatic cancer is a malignant cancer with a high mortality rate. The amount of chymotrypsin C in pancreatic cancer cells is only 20% of that found in normal cells. Chymotrypsin C has been reported to be involved in cancer cell apoptosis, but its effect on pancreatic cancer cell migration is unclear. We performed cell migration scratch assays and Transwell experiments, and found that cell mig...

In this study, we report a reliable technique for the harvest, cultivation and expansion of monoculture of NMU. The NMU were harvested by two methods, directly from the urothelium in vivo and indirectly from the urothelial outgrowths of bladder explant cultures. Primary cultures and subsequent subcultures were propagated in the mixture of media MCDB 153 and Advanced-DMEM, and conditioned medium...

I N T R O D U C T I O N The treatment of epithelial tumors continues to be a major medical challenge due in part to both cellular and noncellular Received 4/19/95; revised 8/23/95; accepted 9/20/95. Supported in part by a research fellowship award from the ASTRO Education and Development Fund, Grants CA56666 and CA23074, and DOE Contract 307190. Financial support does not constitute an endorsem...