L-Methionine-DL-sulfoximine, a glutamate analog known to inhibit glutamine synthetase (GS) and glutamate synthase (GOGAT), allowed nitrogenase biosynthesis by Fratikia strain D11 in presence of NH4$. GS activity, detected in cell-free extracts of D1 1 , was higher in N2-fixing than in nonfixing conditions. These facts suggested that nitrogenase biosynthesis in Frankia was probably regulated by ...

We study the outcome of the amendment voting procedure based on a potentially incomplete preference relation. A decision-maker evaluates candidates in a list and iteratively updates her choice by comparing the status-quo to the next candidate. She favors the status-quo when the two candidates are incomparable according to her underlying preference. Developing a revealed preference approach, we ...

The share of household resources devoted to children is hard to identify, because consumption is measured at the household level, and goods can be shared. Using semiparametric restrictions on individual preferences within a collective model, we identify how total household resources are divided up among household members, by observing how each family member’s expenditures on a single private go...

Mutual diffusion coefficients of chloroquine diphosphate (CDP) in aqueous solutions both without and with ?-cyclodextrin (?-CD) were measured at concentrations from (0.0000 to 0.0100) mol dm?3 298.15 K, using the Taylor dispersion technique. Ternary mutual (Dik) by same technique are reported for CDP + ?-CD K. The presence ? CD led relevant changes process, as showed nonzero values cross-diffus...

This paper studies competition between firms when consumers observe a private signal of their preferences over products. Within the class structures that induce pure-strategy pricing equilibria, we derive are optimal for and those consumers. The firm-optimal policy amplifies underlying product differentiation, thereby relaxing competition, while ensuring purchase preferred product, maximizing t...

We introduce a search model where products differ in horizontal attributes and unobserved quality (“experience goods”), firms can establish reputation. show that the inability of consumers to observe before purchase significantly changes how frictions affect market performance. In equilibrium, higher costs reduce match values increase price but boost firms’ investment product quality. Under pla...

Acute sleep deprivation (SD) alters cardiovascular autonomic control (CAC) and is associated with an increased risk of cardiovascular disorders. However, the effects of partial SD on CAC are unclear. Thus, we aimed to investigate the effects of partial SD on CAC during sleep. We randomized seventeen healthy subjects to a restriction group (RES, n = 8, subjects slept two-thirds of normal sleep t...

PURPOSE To assess the usefulness of noninvasive combined technologies used to observe ocular surface changes in toxicology studies. METHODS Benzalkonium chloride (BAC) at 0.01%, 0.1%, 0.25%, and 0.5% was applied to rat corneas for 11 days. The eye was evaluated macroscopically from day (D)0 to D52. The cornea was examined with the slit lamp, a fluorescein test was performed, and a confocal mi...

Prostate cancer (PC) is the second most common cancer in men. Family history is the major risk factor for PC. Only two susceptibility genes were identified in PC, BRCA2 and HOXB13. A comprehensive search of germline variants for patients with PC has not been reported in Japanese families. In this study, we conducted exome sequencing followed by Sanger sequencing to explore responsible germline ...

Trimethylation of Histone 3 lysine 27 (H3K27me3) is a chromatin modification that is associated with transcriptional repression (Cao et al., 2002; Sarma et al., 2008; Pengelly et al., 2013) [1], [2], [3]. In this article we performed anti-H3K27me3 Chromosomal Immunoprecipitation (ChIP-PCR), to detect the abundance of H3K27me3 marks on Ef1-alpha, cyp26A, HoxC10, HoxD10 and HoxD11 in the Xenopus ...