Acetylcholine (ACh)- and high KCl-stimulated 45Ca uptake into rat uterine segments was inhibited by 3-deazaadenosine (3-DAA) plus homocysteine thiolactone (HCTL), and this inhibitory effect was attenuated by L-methionine (L-Met). Ca-depleted Ringer solution in which uterine muscle had been incubated with L-Met did not enhance the contractile response of another uterine segment to ACh and high K...

The Direct Anonymous Attestation (DAA) scheme provides a means for remotely authenticating a trusted platform whilst preserving the user’s privacy. The protocol has been adopted by the Trusted Computing Group (TCG) in the latest version of its Trusted Platform Module (TPM) specification. In this paper we show DAA places an unnecessarily large burden on the TPM host. We demonstrate how corrupt a...

ABSTRACT Soil attributes may affect the residual activity and impacts of herbicides on non-target organisms. This study aimed to evaluate sulfentrazone herbicide its microbiological parameters Brazilian Savanna soils, as well identify soil that can be used predict in these soils. The experimental design was completely randomized, a 6 x 5 factorial scheme, with 4 replications, being types (Rhodi...

Abstract Background: A major impact of the IL28B gene polymor-phism on response to antiviral therapy in chronic hepatitis C have been described recently by a lot studies. This study aims scrutinize genotypes donors and recipients treatment with INF based or DAA among patients that underwent liver trans-plantation. Aim Study: correlate genotype for had undergone transplantation therapy, Direct A...

Abstract Background Thrombocytopenia can rapidly improve in chronic hepatitis C (CHC) patients receiving direct-acting antiviral agents (DAA). The role of baseline (BL) thrombopoietin (TPO) this phenomenon is unclear. Methods From June 2016 to February 2019, a total 104 CHC DAA, with sustained virologic response and BL thrombocytopenia, at Dalin Tzu Chi Hospital, were enrolled retrospective stu...

With the advent of direct-acting antiviral agents (DAA) in recent few years, hepatitis C virus (HCV) infection has become a curable infectious disease. Successful clearance HCV could lead to improvement both hepatic and extrahepatic outcomes, such as complications cirrhosis, hepatocellular carcinoma, cardiovascular diseases, incident diabetes. However, challenges persist reaching elimination go...

O deslocamento de herbicidas auxínicos para o local não alvo resulta em prejuízos agronômicos e ambientais. Objetivou-se nesta pesquisa avaliar os efeitos doses dos dicamba triclopyr aplicados nas fases fenológicas V2, V4 V8 da cultura do milho. Foram testados parcelas subdivididas, no arranjo 3x5, as aplicações três milho (V2, V8) cinco cada herbicida (0; 4,8; 24; 48; 96 g e.a. ha-1). As aplic...

Background: We aimed at assessing the benefit-to-risk ratio of activated protein C (drotrecogin-alfa activated, DAA) and corticosteroids, given alone or in combination, in patients with septic shock. Methods: We implemented an investigator-led, publicly funded, multicenter, randomized according to a 2 × 2 factorial design, placebo-controlled, double-blind trial in four parallel groups in which ...

BACKGROUND Aim was to determine the dynamics of peripheral blood mononuclear cells (PBMC)- associated total HIV-1 DNA in successfully ART-treated HIV/HCV co-infected patients receiving DAA treatment and to explore possible virological hypotheses underlying the phenomenon. METHODS Longitudinal, single-centre study measuring total HIV-1 DNA before the start of DAA, at the end of treatment (EOT)...

INTRODUCTION For cases with extensive acetabular bone defects, we perform surgery combining the Kerboull-type (KT) plate and bone graft through direct anterior approach (DAA) in primary total hip arthroplasty (THA) requiring acetabular reconstruction as minimally invasive surgery. This paper provides the details of the surgical procedure. METHODS The basic structure of the Kerboull-type plate...