A new method is introduced for parametric modeling of spectral envelopes when only a discrete set of spectral points is given. This method, which we call discrete all-pole (DAP) modeling, uses a discrete version of the Itakura-Saito distortion measure as its error criterion. One result is a new autocorrelation matching condition that overcomes the limitations of linear prediction and produces b...

This paper presents an overview of a collection of recent developed evolutionary algorithms for solving different types of allocation problems under the consideration of several conflicting objectives. These algorithms are: MOEA-DAP, MOMS-GA and the MultiTask Multi-State MOEA. MOEA-DAP is a custom multiple objective evolutionary algorithm for solving design allocation problems. MOEA-DAP conside...

Prior exposure to difficult motor conflicts has been shown to impede later performance in resolving easier conflicts. To determine if similar negative transfer occurred with verbal conflicts, 80 undergraduates resolved conflicts formed by pairi~g seven personal characteristic adjectives. Additional transfer effects associated with moving from easier to more difficult conflicts were also exami~e...

It was earlier hypothesized that the malarial parasite may convert precursors of folate analogues to synthesize de novo inhibitors toxic to itself, but not to the mammalian cell. It was suggested that one such analogue, 2,4-diamino-6-hydroxymethylpteridine (DAP) may be converted to aminopterin (AMP), a known dihydrofolate reductase inhibitor. In the present study, we evaluated the ability of DA...

OBJECTIVES The development of daptomycin resistance in Staphylococcus aureus is associated with clinical treatment failures. The mechanism(s) of such resistance have not been clearly defined. METHODS We studied an isogenic daptomycin-susceptible (DAP(S)) and daptomycin-resistant (DAP(R)) S. aureus strain pair (616; 701) from a patient with relapsing endocarditis during daptomycin treatment, u...

Infections are a devastating complication of titanium alloy orthopedic implants. Current therapies include antibiotic-impregnated bone cement and antibiotic-containing coatings. Daptomycin (DAP) (1) is a novel peptide antibiotic that penetrates the cell membranes of Gram-positive bacteria. Few DAP-resistant strains have appeared so far. We hypothesized that when DAP covalently bonded via a flex...

Dr. Antonino Carbone, Division of Pathology, Centro di Riferimento Oncologico, Via Pedemontana Occidentale, I-33081 Aviano (Italy) The cytochemical demonstration of dipeptidyl amino peptidase IV (DAP IV) in human peripheral blood lymphocytes was first described by Lojda [1]. Subsequent reports have shown that this ‘exopepti-dase’ has an apparent restriction to a particular T-cell subset, in tha...

The cell wall compositions of two strains of Corynebacterium bovis were found to differ: one contained lysine, rhamnose, mannose, and glucose, the other meso-alpha, epsilon, diaminopimelic acid (DAP), arabinose, galactose, and mannose. The walls of a strain of C. nephridii were characterized by l-DAP and galactose. Those of a strain of C. paurometabolum and of two strains of "lipophilic diphthe...

Dorsal agenesis of the pancreas (DAP) is an uncommon embryological abnormality where there is absence of the distal pancreas. DAP is mostly asymptomatic, but common presenting symptoms include diabetes mellitus, abdominal pain, pancreatitis, enlarged pancreatic head, and, in a few cases, polysplenia. MRCP and ERCP are the gold standard imaging techniques to demonstrate the absence of the dorsal...