A clinical, radiological and statistical survey has been made of decompression sickness during the construction of the Dartford Tunnel. Over a period of two years, 1,200 men were employed on eight-hour shifts at pressures up to 28 pounds per square inch (p.s.i.). There were 689 cases of decompression sickness out of 122,000 compressions, an incidence of 0-56%. The majority of cases (94-9 %) wer...

Vascular bubble formation after decompression contributes to endothelial injuries which form the basis for the development of decompression sickness (DCS). Nitric oxide (NO) is a powerful vasodilator that contributes to vessel homeostasis. It has been shown that NO-releasing agent may reduce bubble formation and prevent serious decompression sickness. The use of sildenafil, a well-known, phosph...

A serious diving accident can occur in recreational diving even in countries where diving is not very popular due to the fact that diving conditions there are not as great as in some tropical diving locations. The estimated number of injured divers who need recompression treatment in European hyperbaric facilities varies between 10 and 100 per year depending on the number of divers in the popul...

Despite state-of-the-art hyperbaric oxygen (HBO) treatment, about 30% of patients suffering neurologic decompression sickness (DCS) exhibit incomplete recovery. Since the mechanisms of neurologic DCS involve ischemic processes which result in excitotoxicity, it is likely that HBO in combination with an anti-excitotoxic treatment would improve the outcome in patients being treated for DCS. There...

(figure). Capillary loops were not thickened and no trichrome positive deposits were seen. The tubules, interstitium, and blood vessels were all normal. Immunofluorescence studies were negative for all immunoglobulins, fibrin, and g-IC. Electron microscopy showed diffuse foot process fusion of the podocytes (see figure) with no electron dense deposits. The basement membrane was normal. He recei...

Analysis of urine electrolytes obtained during saturation excursion dives of four divers to depths equivalent to 800 and 1000 feet of sea water snowed in all cases during decompression an increase in urinary CO2 excretion and calcium excretionIn two subjects who developed symptoms of decompression sickness manifested in poorly localized muscle aches and stiffness of joints which did not respond...

INTRODUCTION A perception exists in aerospace that a brief interruption in a 100% oxygen prebreathe (PB) by breathing air has a substantial decompression sickness (DCS) consequence. The consequences of an air break during PB on the subsequent hypobaric DCS outcomes were evaluated. The hypothesis was that asymmetrical and not symmetrical nitrogen (N2) kinetics was best to model the distribution ...