Iodide is concentrated to a much lesser extent by papillary thyroid carcinoma as compared with the normal gland. The Na+/I- symporter (NIS) is primarily responsible for the uptake of iodide into thyroid cells. Our objective was to compare NIS mRNA and protein expression in papillary carcinomas with those in specimens with normal thyroid. Northern blot analysis revealed a 2.8-fold increase in th...

The aim of report is to present a case of a rare diffuse sclerosing variant of a papillary thyroid carcinoma. A 15-year old girl referred for ultrasound examination because of painless thyroid swelling lasting 10 days before. An ultrasound of the neck showed diffusely changed thyroid parenchyma, without nodes, looking as lymphocytic thyroiditis Hashimoto at first, but with snow-storm appearance...

INTRODUCTION Thyroglossal duct cyst carcinomas are extremely rare and their clinical presentation is similar to that of benign cysts. The diagnosis is based on physical examination, laboratory tests, and most importantly multiple imaging techniques (ultrasonography, computed tomography and magnetic resonance imaging), and fine needle aspiration cytology. PRESENTATION OF CASE We report a very ...

Papillary thyroid carcinoma (PTC) associated with familial adenomatous polyposis (FAP) is rare. It is usually associated with the cribriform-morular variant of PTC, with unusual patterns on detailed histology examination. This variant is known to have a good prognosis. Papillary thyroid carcinoma associated with FAP commonly occurs in females in their 30s and rarely in the elderly. We report a ...

Using immunohistochemistry, Fas/Apo-1 protein expression was investigated in thyroid cancers of 67 patients. Thyroid biopsies from twenty eight patients with benign thyroid diseases were also examined. The patients with thyroid cancer manifested a variable histology of the cancer, including 14 patients with follicular carcinoma, 48 with papillary carcinoma, 5 patients with medullary carcinoma. ...

Well differentiated papillary carcinoma of thyroid frequently metastasizes to regional lymph nodes and the patients usually present with cervical or mediastinal lymphadenopathy. In this article, we report a case of papillary thyroid carcinoma with hepatic metastasis presenting as liver mass in absence of lymph nodal metastasis, a presentation not previously reported to the best of our knowledge.

Papillary carcinoma of thyroid is an uncommon malignancy among young children. Its biological behaviour and prognosis is different from that of adults. We present a case report of a 16 years old child presented with swelling in midline of neck. On fine needle aspiration biopsy (FNAC) papillary carcinoma of thyroid was detected and the patient underwent subtotal thyroidectomy followed by radioio...

An elderly otherwise healthy male presented with a mass in thigh. Fine needle aspiration cytology (FNAC) revealed features of papillary carcinoma of thyroid, suggesting secondary deposits. Later the patient was clinically evaluated. There was no obvious thyromegaly both clinically and sonologically. The patient was followed up. One month after initial presentation, he came with an enlarged cerv...

Ligands for peroxisome proliferator-activated receptor gamma (PPARgamma) induce apoptosis and exert antiproliferative effects on several carcinoma cell lines. The present study investigates the expression of PPARgamma and the possibility that agonists for PPARgamma also inhibit the growth of human thyroid carcinoma cells. We examined this hypothesis using six cell lines, designated BHP thyroid ...