Vestibular activation is found in diverse cortical areas. To characterize the pathways and types of signals supplied to cortex, we recorded responses to rotational and/or translational stimuli in the macaque thalamus. Few cells responded to rotation alone, with most showing convergence between semicircular canal and otolith signals. During sinusoidal rotation, thalamic responses lead head veloc...

The cerebellar and vestibular nuclei consist of a heterogeneous group of inhibitory and excitatory neurons. A major proportion of the inhibitory neurons provides a GABAergic feedback to the inferior olive, while the excitatory neurons exert more direct effects on motor control via non-olivary structures. At present is is not clear whether Purkinje cells innervate all types of neurons in the cer...

Human Brain Mapping 2007 Diffusion Tensor Imaging Enables Robust Mapping of the Deep Cerebellar Nuclei Bennett A. Landman , Annie X. Du , Wade D. Mayes , Jerry L. Prince a, c, , Sarah H. Ying d, e a Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, USA b Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, U...

Central positional nystagmus arises due to disruption of brainstem or cerebellar vestibular networks. Most patients with central had lesions focal diffusion pontine lesion. From a clinical perspective, the presence is thus highly predictive in posterior fossa, including apparatus, nuclei, and midline structures within vermis. We experienced infarction dentate nucleus.