A series of 5-carbomethoxybenzoxazole derivatives (6a-t) were prepared by using methyl-p-hydroxybenzoate. The identity of the compounds was confirmed on the basis of their elemental analysis and spectral data. In anti-MES test compounds 6b, 6d, 6h, 6j, 6m, 6p, 6q and 6s showed potent activity parallel to lipophilicity. Compounds 6b, 6d, 6k, 6n and 6s successfully passed the rotorod test without...

Genotyping, using plasma proteins or DNA polymorphisms or both, was carried out on 30 families selected through probands with Von Recklinghausen disease. The data provide additional evidence for the exclusion of loci on chromosomes 3 and 5, and chromosome arms 1q, 2p, 4p, 4q, 6q, 7p, 9q, 11p, 11q, and 14q. There was no evidence for genetic heterogeneity at D1S1 (DNF15S2) on chromosome arm 3p, u...

We have measured the linear polarization correlation between the two photons from the 7 S~-6 P~-6 So cascade of Hg . The results were used to evaluate Freedman's version of the Bell inequality, 5 ~0. Our result is 6~+=+0.046+0.014, in clear violation of the inequality and in excellent agreement with the quantum mechanical prediction, 6Q+ =+ 0.044 +0.007. An important feature of the experiment w...

Background: Male infertility is a Multifactorial syndrome encompassing a wide variety of disorders. In more than half of infertile men, the cause of their infertility is unknown (idiopathic) and could be congenital or acquired. Globozoospermia, also called round-headed spermatozoa, is a rare disease with incidence< 0.1% among male infertile patients. The most prominent feature of globozoospermi...

Background: Successful IVF process is limited by factors such as oocyte quality. Oocyte quality can be defined as its abilities to be fertilized, mature and give rise to normal offspring and it is dependent on nuclear maturation and cytoplasm maturation. Damage to mitochondrial DNA (mtDNA) has been described in oocytes in IVF failure women that decrease cytoplasmic quality because Mitochondria ...

For a positive integer n, let G be Kn if n is odd and Kn less a one-factor if n is even. In this paper it is shown that, for non-negative integers p, q and r, there is a decomposition of G into p 4-cycles, q 6-cycles and r 8-cycles if 4p+6q+8r = |E(G)|, q = 0 if n < 6 and r = 0 if n < 8.