BACKGROUND The pathophysiology and appropriate pharmacological interventions for delusional infestation remain unknown. CASE PRESENTATION Here, we report a case of primary delusional infestation successfully treated with aripiprazole. We performed functional magnetic resonance imaging (fMRI) to investigate brain structures and functional modifications. Before antipsychotic treatment, pre- ver...

This paper describes a multi-dimensional study of non-organic hallucinatory states in the over-sixties. The subjects totalled 43 with no signs of obvious dementia or sustained confusion. Eleven biological, socio-psychological factors and 15 aspects of the clinical picture were assessed at the initial interview. Clinical symptoms were followed under medical treatment. Thirty eight subjects were ...

Amphetamine abusers are shown to have significant cognitive impairments as well as delusional disorders. We present a 17-year-old man who was admitted to the toxicology emergency department with amphetamine overdose. Along with the classic signs and symptoms of overdose including mydriasis, tachycardia, hypertension, sweating and severe agitation, his urine toxicology screen test was found to b...

Anxiety and worry may be the key emotions involved in the formation of delusions of persecution, though other affective processes (depression, anger) may have some contribution. Prospective and retrospective clinical studies conducted have shown that in most cases, symptoms of anxiety, worry, depression and irritability preceding the positive symptoms with 2-4 weeks. AIMS: The study was based o...

BACKGROUND Although antipsychotic medication still represents the treatment of choice for schizophrenia, its objective impact on symptoms is only in the medium-effect size range and at least 50% of patients discontinue medication in the course of treatment. Hence, clinical researchers are intensively looking for complementary therapeutic options. Metacognitive training for schizophrenia patient...

INTRODUCTION Delusional parasitosis (DP) is a condition in which a person has the unshakeable and mistaken belief of being infested with parasites. PATIENTS AND METHODS All patients with DP seen by the Division of Dermatology, Department of Medicine, National University Hospital were reviewed. The case histories of 8 Chinese patients are discussed. RESULTS The patients with DP were predomin...

Recent debates about deworming school-aged children in East Africa have been described as the 'Worm Wars'. The stakes are high. Deworming has become one of the top priorities in the fight against infectious diseases. Staff at the World Health Organization, the Gates Foundation and the World Bank (among other institutions) have endorsed the approach, and school-based treatments are a key compone...