Among the neurologic complications of malaria, acute inflammatory demyelinating polyradiculoneuropathy is a rarely reported phenomenon. We describe a patient with acute inflammatory demyelinating polyradiculoneuropathy following malaria in a 26-year-old traveler to an endemic area and review the clinical features of all 23 previously reported patients. Malarial infection should be considered as...

Dolichoectasis is a dilative arteriopathy that can be seen in intracranial vertebral and basilar arteries people with hypertension advanced age. Although most cases are asymptomatic, cerebral ischemia, bleeding or compression may occur. The diagnosis of VBD was made by catheter angiography before; while MR the sensitive imaging method today. In addition, differential aneurysm/other vascular pro...

Human peripheral demyelinating diseases, such as Guillain-Barré syndrome (GBS), are characterized by inflammation and demyelination in the peripheral nervous system. Similarities in the pathology between GBS and the animal model of experimental autoimmune neuritis (EAN) indicate that autoimmune responses are involved in both diseases. This article summarizes the general aspects of the EAN model...

Neurological complications of inflammatory bowel diseases (i.e., ulcerative colitis and Crohn's disease) can be summarized as a combination of neuromuscular manifestations, cerebrovascular and demyelinating diseases that can be seen in approximately 3% of patients. In addition, asymptomatic cerebral white matter lesions may be detected in these patients. Clustering of diseases within families m...

Abstract Demyelinating diseases can be driven by CD4 T cells specific for self-antigen derived from myelin in the central nervous system (CNS). Mouse models utilizing peptide induction protocols may restrict breadth of cell specificity. Here, we compare mice induced with a fragment oligodendrocyte glycoprotein (MOG), recombinant extracellular domain (ECD), and full-length MOG protein, which inc...

Acute hemorrhagic leukoencephalitis (AHLE) is a rare demyelinating disease characterized by an acute rapidly progressive fulminant inflammation of the white matter. In this case report, we introduce a case of AHLE in children with an interesting and lengthy process and successful treatment.A previously healthy 13-year-old girl was admitted to the hospital because of fever and loss of consciousn...

Background and Methods: Acquired demyelinating syndromes (ADS) encompass distinct entities occur in approximately 1/100,000 children. While the use of high dose intravenous corticosteroids is well-established, agreement on steroid taper type second line therapy lacking. Therefore, this study performed from July 2018 to June 2020 aimed at developing a national consensus management ADS pediatric ...