A dent is a gross distortion of the pipe cross-section. Dent depth is defined as the maximum reduction in the diameter of the pipe compared to the original diameter. Pipeline dent finite element (FE) simulation and theoretical analysis are conducted in this paper to develop an understanding of the geometric characteristics and strain distribution in the pressurized dented pipe. Based on the res...

OCRL mutations are associated with both Lowe syndrome and Dent-2 disease, two rare X-linked conditions. Lowe syndrome is an oculo-cerebro-renal disorder, whereas Dent-2 patients mainly present renal proximal tubulopathy. Loss of OCRL-1, a phosphoinositide-5-phosphatase, leads in Lowe patients' fibroblasts to phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) accumulation, with defects in F-actin...

Two experiments were conducted to measure the energy and nutrient digestibilities in NutriDense corn and other cereal grains. An additional objective was to evaluate the effect of balancing diets with AA on the values measured for DE and ME of corn varieties. In Exp. 1, 6 growing pigs were fitted with a T-cannula in the distal ileum and allotted to a 6 x 6 Latin square design to measure apparen...

The presence of odontoblasts in dentinal tubules has been noted by numerous investigators. One of the first to describe their presence was B. Orban (l Dent Res 20:553-557, 1941). The cells were in tubules associated with forceps marks on the root surfaces. Odontoblasts in dentinal tubules have been reported due to various types of trauma to pulps. Cavity preparation (V. E. JAMES and I. SCHOUR, ...

Two mechanical methods have been developed for the characterization of the flexibility of protective gloves, a key factor affecting their degree of usefulness for workers. The principle of the first method is similar to the ASTM D 4032 standard relative to fabric stiffness and simulates the deformations encountered by gloves that are not tight fitted to the hand. The second method characterizes...

Dent disease has multiple defects attributed to proximal tubule malfunction including low-molecular-weight proteinuria, aminoaciduria, phosphaturia, and glycosuria. To understand the changes in kidney function of the Clc5 chloride/proton exchanger gene knockout mouse model of Dent disease, we examined gene expression profiles from proximal S1 and S2 tubules of mouse kidneys. We found many chang...

Methods We developed a questionnaire based on the WHO glove use pyramid. The pyramid was used as campaign material for the most recent national hand hygiene campaign (end of campaign May, 2009). The final questionnaire contained 36 glove use indications with four response alternatives: “no gloves indicated”, “non-sterile gloves indicated”, “sterile gloves indicated” and “I do not know”. Demogr...

Sensory feedback from cutaneous mechanoreceptors in the fingertips is important in effective object manipulation, allowing appropriate scaling of grip and load forces during precision grip. However, the role of mechanoreceptor subtypes in these tasks remains incompletely understood. To address this issue, psychophysical tasks that may specifically assess function of type I fast-adapting (FAI) a...

With increasing awareness of the possibility of exposure to blood borne pathogens during surgery, surgeons are becoming more and more concerned with protecting themselves against such exposures. Wearing of double pair of gloves is one method to protect against such exposures. The present study was carried out to evaluate the incidence of perforation of single and double gloves during surgery. 1...