budd-chiari syndrome (bcs) refers to thrombosis of hepatic veins as well as intrahepatic or suprahepatic inferior vena cava. we present for the first time a case of possible occurrence of budd- chiari syndrome with the history of depot medroxy progesterone acetate (dmpa) injections in a 33-yearold iranian woman. an underlying disorder can be identified in most of patients with bcs. many of thes...

We have established a continous cell line (G1) in which the tyrosine hydroxylase specific activity is increased as much as 50-100-fold in response to dexamethasone. This response is specific for the glucocorticoid class of steroid hormones; it is elicited by dexamethasone, corticosterone, and triamcinolone, but not by estradiol, testosterone, progesterone, or deoxycorticosterone acetate. The in...

Objective: To examine the relationship between progestin-only contraception and breast cancer, and to make recommendations regarding contraception for the breast cancer survivor. Outcome: Incidence of breast cancer among users of progestin-only contraception. Evidence: PubMed and Medline databases were searched using the terms “breast cancer” and “progesterone,” “contraception,” “depot medroxyp...

Objective: To examine the relationship between progestin-only contraception and breast cancer, and to make recommendations regarding contraception for the breast cancer survivor. Outcome: Incidence of breast cancer among users of progestin-only contraception. Evidence: PubMed and Medline databases were searched using the terms “breast cancer” and “progesterone,” “contraception,” “depot medroxyp...

The progesterone receptor (PR) with its isoforms and ligands are involved in breast tumorigenesis and prognosis. We aimed at analyzing the respective contribution of PR isoforms, PRA and PRB, in breast cancer cell proliferation in a new estrogen-independent cell based-model, allowing independent PR isoforms analysis. We used the bi-inducible human breast cancer cell system MDA-iPRAB. We studied...

The aim of this study was to examine whether increased frequency of luteinizing hormone (LH) pulses influences luteal progesterone (P4) secretion by measuring progesterone concentrations at the secreted (caudal vena cava) and circulating levels (jugular vein) in lactating dairy cows. Cows received six intravenous administrations of 2.5 μg of GnRH (gonadorelin acetate, n=4) or 2 ml saline (n=3) ...

BACKGROUND Depot medroxyprogesterone acetate (DMPA) is a very popular hormonal contraceptive. Unpredictable bleeding disturbances are the main reasons for discontinuation and may be mediated through endometrial hormone receptors. This study was aimed to compare the expression of progesterone and estrogen receptors in the endometrium of bleeding DMPA users with that of amenorrhoeic DMPA users. ...