AIMS AND METHOD To establish if participants with schizophrenia receiving depot antipsychotics had less insight than similar participants receiving oral atypical antipsychotics.We assessed the difference between these two groups. RESULTS Participants on oral antipsychotics had greater insight than those on depot antipsychotics (ITAQ, P=0.01). In the multiple regression analysis, only receiving ...

AIMS AND METHOD To establish if participants with schizophrenia receiving depot antipsychotics had less insight than similar participants receiving oral atypical antipsychotics.We assessed the difference between these two groups. RESULTS Participants on oral antipsychotics had greater insight than those on depot antipsychotics (ITAQ, P=0.01). In the multiple regression analysis, only receiving ...

Metaheuristics are widely employed to solve hard optimization problems, like vehicle routing problems (VRP), for which exact solution methods impractical. In particular, local search-based metaheuristics have been successfully applied the capacitated VRP (CVRP). The CVRP aims at defining minimum-cost delivery routes a given set of identical vehicles since each only travels one route and there i...

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Intramuscular formulations of antipsychotics can be sub-divided into two groups on the basis of their pharmacokinetic features: short-acting preparations and long-acting or depot preparations. Short-acting intramuscular formulations are used to manage acute psychotic episodes. On the other hand, long-acting compounds, also called "depot", are administered as antipsychotic maintenance treatment ...

There are subtle, and yet critical and unique differences that distinguish the depot maintenance, repair, and overhaul (MRO) domain from production manufacturing. These differences motivate the need for more efficient ways to capture the essence of the depot MRO domain dynamics. The authors provide an informal characterization of the depot MRO by highlighting some of the major differences. Alon...

This paper addresses a rollon–rolloff waste collection vehicle routing problem which involves large containers that collect huge amounts of waste from construction sites and shopping malls. In this problem, vehicles could only move one container at a time between customers’ locations, a depot, a disposal center, and a recycling center site. Other than a disposal center, a recycling ...

This paper studies the multi-depot joint distribution vehicle routing problem considering energy consumption with time-dependent networks (MDJDVRP-TDN). Aiming at where travel time depends on variation characteristics of road network speed in area, influence and relationship between load fuel consumption, a optimization model is established to minimize sum fixed cost, cost window penalty cost. ...

OBJECTIVE To find the time of the serum gonadotropin peak after depot leuprolide injection in children and to show that depot leuprolide therapy can be monitored by measuring serum luteinizing hormone (LH) immediately after injections. STUDY DESIGN We measured concentrations of leuprolide, LH, and follicle-stimulating hormone (FSH) at multiple time points before and after the first dose of de...