نتایج جستجو برای: derived neurotrophic factor
تعداد نتایج: 1261660 فیلتر نتایج به سال:
Zuckerkandl’s organ (ZK) is an extra adrenal para-ganglion and has the ability to express glial cell line derived neurotrophic factor (GDNF) and transforming growth factor (TGF). It is also a source of dopamine and norepinephrine. In the present study, the neuroprotective and restorative potential of ZK was studied by transplanting it into the striatum of adult rats either before or after the i...
Abbreviations: GDNF, glial cell line-derived neurotrophic factor; BDNF, brain-derived neurotrophic factor; DA, dopaminergic; 6-OHDA, 6-hydroxydopamine; Ad, adenoviral; SN, substantia nigra pars compacta; CNS, central nervous system; MFB, medial forebrain bundle; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+, 1-methyl-4-phenyl pyridinium; MAO-B, monoamine oxidase; TH, tyrosine hydroxy...
Apomorphine, the catechol-derived dopamine D1/D2 receptor agonist, is currently in use as an antiparkinsonian drug. It has previously been reported that apomorphine was able to elicit expression of the enzyme tyrosine hydroxylase, a marker for DA neurons, in the fetal rat cerebrocortical cultures whilst in the presence of brain-derived neurotrophic factor. The present study demonstrated that tr...
objective(s)progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. in recent years, the neuroprotective effects of progesterone have attracted growing interest. glial cell line-derived neurotrophic factor (gdnf), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...
Previous studies suggest that the delivery of neurotrophic factors secreted from adipose stromal cells (ASC) protect the brain from 6-hydroxydopamine (6-OHDA)-induced neurotoxicity. However, it remains unclear which secreted neurotrophic factor has an important role in protecting 6-OHDA-treated neurons. Through the use of antibodies in this study, we demonstrated that specific neutralization of...
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