OBJECTIVE (31)P magnetic resonance spectroscopy (MRS) is useful for evaluating metabolic disturbances in dermatomyositis (DM). However, short-term alterations of metabolic parameters such as Pi/PCr (inorganic phosphate/phosphocreatine) have not been assessed in detail, although they may reveal insights into the origin of the known long-term changes. We therefore performed real-time functional (...

Achieving total glioma resection represents a major challenge to neurosurgeons with no distinct margin between tumor and surrounding brain tissue. Many imaging methods are employed in surgery visualization and resection control. We performed this meta-analysis to assess the diagnosis value of intraoperative ultrasound and judged whether ultrasound is a suitable tool in detecting glioma residual...

OBJECTIVE To evaluate whether clinicians differ in how they evaluate and interpret diagnostic test information. DESIGN Systematic review. DATA SOURCES MEDLINE, EMBASE and PsycINFO from inception to September 2013; bibliographies of retrieved studies, experts and citation search of key included studies. ELIGIBILITY CRITERIA FOR SELECTING STUDIES Primary studies that provided information on...

The number of patients with schizophrenia has increased over the past decade. Previously, many studies have been performed to establish its diagnostic criteria, prophylactic methods, and effective therapies. In this study, we analyzed whether the ratios of DNA methylation in CpG islands of the Shati/Nat8l is decreased in model mice of schizophrenia-like phenotype using genomic DNA collected fro...

In order to examine the excitation and ionization mechanism of extraplanar diffuse ionized gas (DIG) we have obtained optical longslit spectra of seven edge-on spiral galaxies. In four objects the brightest emission lines can be traced out to distances of typically 1.5 kpc above the disk. For NGC 1963 and NGC 3044 line ratios such as [N ii] λ6583/Hα or [S ii] λ6717/Hα as well as [O iii] λ5007/H...

The main objective of the present study was to evaluate the diagnostic value (clinical application) of brain measures and cognitive function. Alzheimer and multi-infarct patients (N = 30) and normal subjects over the age of 50 (N = 40) were submitted to a medical, neurological and cognitive investigation. The cognitive tests applied were Mini-Mental, word span, digit span, logical memory, spati...

AIMS Heart failure with a preserved ejection fraction (HF-PEF) remains a difficult clinical diagnosis. The aim of this study was to test the utility of established criteria to classify patients with HF-PEF. We prospectively enrolled patients into one of five groups across a spectrum of cardiac disease and applied three different criteria for HF-PEF and calculated diagnostic metrics. METHODS A...

OBJECTIVES This multicenter study examines the performance of the Manchester Triage System (MTS) after changing discriminators, and with the addition use of abnormal vital sign in patients presenting to pediatric emergency departments (EDs). DESIGN International multicenter study. SETTINGS EDs of two hospitals in The Netherlands (2006-2009), one in Portugal (November-December 2010), and one...

background since iran is one of the malaria endemic areas, diagnosis of this disease is important. although the microscopic study of stained peripheral blood smears is as a gold standard of malaria diagnosis, this method requires a microscope, the equipment, and trained people. because of some problems associated with microscopic method in some situations, rapid diagnostic test (rdts) can be a ...