A two-step sequence for the synthesis of various 3,4-dihydro-2H-1,3-thiazines is presented. In the first step, 2H-1,3-thiazines were prepared by a new multicomponent reaction (MCR). Starting from β-chlorovinyl aldehydes, this MCR offers an efficient and facile access to 2,2-dialkyl- and 2-alkyl-2-aralkyl-5,6-diaryl-2H-1,3-thiazines. The potential of these products in subsequent reactions was ve...

p-silylated n,n-dialkyl amines (5) were easily synthesized in good to excellent yield from aldehydes (1), trimethylsilyldialkylamines (2), and trimethylsilylmethylmagnesium chloride (4) in the presence of 5 m lithium perchlorate solution in diethyl ether. the reaction of (2) with aldehyde proceeded smoothly in the lici0 , to give the imimum salt (3). addition of trimethylsilylmethylrnagnesium c...

Maltose as an efficient, available, cheap and eco-friendly catalyst has been applied for the synthesis of 3,4,5-substituted furan-2(5H)one derivatives via a one-pot three-component reaction of arylamines, aromatic aldehydes and dialkyl acetylenedicarboxylates in water. This method has notable advantages in terms of simple workup, no need for column chromatography, short reaction time and high y...

Some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. The reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. All the synthesized compounds were characterized by their physical and spectral data.

Maltose as an efficient, available, cheap and eco-friendly catalyst has been applied for the synthesis of 3,4,5-substituted furan-2(5H)one derivatives via a one-pot three-component reaction of arylamines, aromatic aldehydes and dialkyl acetylenedicarboxylates in water. This method has notable advantages in terms of simple workup, no need for column chromatography, short reaction time and high y...

A convenient synthesis of different types of polyfunctional dihydropyrrol-2-ones via one-pot four component reactions of formaldehyde, dialkyl acetylenedicarboxylates and amines, catalyzed by trichloroacetic acid (Cl3CCO2H) at room temperature has been investigated. The significant advantages of this synthetic method are mild reaction conditions, available and inexpensive material, short reacti...

An asymmetric oxa-Michael/Michael cascade reaction of p-quinols and α,β-unsaturated aldehydes provides access to hindered dialkyl ethers. A highly enantioselective oxa-Michael addition of a tertiary alcohol precedes an intramolecular cyclohexadienone desymmetrization, which allows for the concomitant formation of four contiguous stereocenters in a single step. The highly functionalized bicyclic...

The molecular structure of the bulky primary silane, (Me(3)Si)(3)CSiH(3), in the gas phase has been determined by electron diffraction. Photolysis of (Me(3)Si)(3)CSiH(3) affords a convenient route to the bulky dialkyl disilane, [(Me(3)Si)(3)CSiH(2)](2), which is the first 1,2-dialkyldisilane to be structurally characterised by single-crystal X-ray diffraction. The disilane has an unusually larg...

A facile synthesis of 2-amino-1,3-oxazoles via CuI -catalyzed oxidative cyclization of enamines and N,N-dialkyl formamides has been developed. The reaction proceeds through an oxidative C-N bond formation, followed by an intramolecular C(sp2 )-H bond functionalization/C-O cyclization in one pot. This protocol provides direct access to useful 2-amino-1,3-oxazoles and features protecting-group-fr...

Antiwear additives are added to engine oils in the form of Zinc dialkyl dithiophosphates (ZDDPs). They form an antiwear (bibochemical) film on the rubbing surfaces. High resolution P and S L-edge X-ray absorption near edge (XANES) spectroscopy has been used to characterize the chemical nature of the films formed under air and inert atmosphere. The total electron yield and fluorescence yield det...