The influence of acute coronary occlusion on systolic and diastolic left ventricular pressurevolume relations was studied in 10 patients undergoing percutaneous transluminal coronary angioplasty (PTCA). Pressure-volume relations were obtained by conductance catheter and micromanometer techniques and with volume load altered by transient inferior vena caval occlusion. End-systolic and end-diasto...

In coronary sclerotic patients with a fixed coronary vascular resistance, coronary blood flow is to be directly regulated by perfusion pressure. In this report, an analysis of perfusion pressure was carried out regarding coronary blood flow, myocardial oxygen consumption, and myocardial oxygen supply. Fourteen patients with coronary sclerosis were studied. In resting state, mean diastolic press...

Though many consider the magnitude of respiratory sinus arrhythmia as an index of cardiac vagal control, its physiological origins remain unclear. One influential model postulates that the systolic pressure rise within a given beat stimulates the baroreflex arc to adjust the following heart period such that diastolic pressure is "stabilized" and hence displays lesser fluctuation. Accordingly, t...

BACKGROUND Good blood pressure control reduces the risk of long-term complications of diabetes; however, most people with diabetes do not achieve recommended blood pressure targets. OBJECTIVE To quantify the relationships between patient and practice factors and blood pressure in patients with type 2 diabetes. METHODS A cross-sectional study was carried out in 42 general practices in Nottin...

Higher diastolic pressure predicted better survival in men 75 years or older in two prior analyses in the Rancho Bernardo population. Diastolic change was implicated as a possible explanation. We studied this by assessing survival according to blood pressure change in 795 men and women aged 75 years and older at the time of a second measurement taken an average of 11 years after the first, who ...

introduction: hypertension is described as one of the risk factors for cardiovascular disease. the prevalence of hypertension is growing among developing countries. in this study, the prevalence of hypertension was studied in individuals who referred to blood transfusion center of ilam city. materials and methods: the present descriptive analytical study was performed based on available data. t...

We analyzed the relationship between diastolic coronary artery pressure and flow in the canine coronary bed, using an electrical analog model of the coronary circulation based on the theory of critical closure. The model contains a voltage-dependent nonlinear resistance and capacitance. The behavior of the resistive element was described using experimental diastolic pressure-flow curves obtaine...

BACKGROUND Previous experimental studies have shown that nitric oxide (NO) modulates cardiac function by an abbreviation of systolic contraction and an enhancement of diastolic relaxation. However, the response to NO donors of patients with severe pressure-overload hypertrophy and diastolic dysfunction is unknown. METHODS AND RESULTS Intracoronary NO donors were given to 17 patients with seve...