A new nanocomposites series of polypyrrole/reduced graphene oxide (PPy/rGO) and covalently bonded with aryl 4-carboxybenzene diazonium salt (PPy/rGO-aryl-COOH) were prepared by simple one-step chemical oxidative synthesis. Spin coating technique was used to deposit the as-prepared on BOPET substrate for testing their chemiresistive sensitivity properties towards online detection (NO2) vapors at...

The response of guinea pig macrophages to migration inhibitory factor (MIF) is altered by several chemical treatments. Treatment of macrophages with the diazonium salt of sulfanilic acid (5 x 10(-6) to 4 x 10(-4) M) significantly increases the response of these cells to MIF. Treatment with acetic anhydride also augments the response of these cells to MIF. The latter finding suggests that altera...

Contact mode atomic force microscopy (AFM) was used to intentionally scratch a monolayer deposited on a pyrolyzed photoresist film (PPF). The force was set to completely remove the monolayer but not to damage the underlying PPF surface. A line profile determined across the scratch with tapping mode AFM permitted determination of the monolayer thickness from the depth of the scratch. A statistic...

Azoproteins, obtained by the coupling of diazonium ions with the histidyl, tyrosyl, and lysyl groups of proteins, have continued to be materials of utility since their early investigation (1). The ease with which proteins can be modified by this procedure, the variety of aromatic amines that can be used, and the correlation that can be made between the chemical structure of the introduced group...

Microcin SF608 (I) is a member of the aeruginosin serine protease inhibitors (Figure 1). This novel class of cyanobacterial non-ribosomal peptides exhibits a strong inhibitory activity against pharmaceutically relevant serine proteases such as thrombin or trypsin. The aeruginosins share a common 2-carboxy-6-hydroxyoctahydroindole (Choi) core fragment. We present a synthetic strategy towards mic...