BACKGROUND AND PURPOSE We hypothesized that, in acute cerebral ischemic stroke, anisotropic diffusion increases if T2 signal intensity is not substantially elevated and decreases once T2 hyperintensity becomes apparent. Our purpose was to correlate fractional anisotropy (FA) measurements with the clinical time of stroke onset, apparent diffusion coefficients (ADC), and T2 signal intensity. ME...

PURPOSE We aimed to compare two different methods of region of interest (ROI) demarcation and determine interobserver variability on apparent diffusion coefficient (ADC) in breast lesions. METHODS Thirty-two patients with 39 lesions were evaluated with a 3.0 Tesla scanner using a diffusion-weighted sequence with several b-values. Two observers independently performed the ADC measurements usin...

BACKGROUND AND PURPOSE Diffusion-weighted (DW) MR imaging is a means to characterize and differentiate morphologic features, including edema, necrosis, and tumor tissue, by measuring differences in apparent diffusion coefficient (ADC). We hypothesized that DW imaging has the potential to differentiate recurrent or progressive tumor growth from treatment-induced damage to brain parenchyma in hig...

Introduction: Both diffusion tensor and diffusion weighted MRI have been used extensively in the evaluation of neurological disorders including stroke, Alzheimer’s disease, and multiple sclerosis [1 – 3]. More recently, interest has grown in the use of diffusion MRI to evaluate and predict response to therapy in various cancers [4 – 6]. Diffusion tensor imaging, which is most useful in the brai...

We have reported that the apparent diffusion coefficient (ADC) was correlated with bone mineral density, but the relation between the restricted diffusion of the water molecules and the trabecular bone structure was unclear. The purpose of our study is to clarify this relationship using two component analyses with an original phantom. With an increase in the interspace area of the simulated tra...

PURPOSE To establish the utility of apparent diffusion coefficient (ADC) entropy in discrimination of benign and malignant adnexal lesions, using histopathology as the reference standard, via comparison of the diagnostic performance of ADC entropy with mean ADC and with visual assessments of adnexal lesions on conventional and diffusion-weighted sequences. MATERIALS AND METHODS In all, 37 adu...

Diffusion tensor imaging (DTI) histogram metrics are correlated with clinical parameters in cerebral small vessel diseases (cSVD). Whether ADC histogram parameters derived from simple diffusion weighted imaging (DWI) can provide relevant markers for long term studies of cSVD remains unknown. CADASIL patients were evaluated by DWI and DTI in a large cohort study over a 6-year period. ADC histogr...

PURPOSE The purpose of this study was to diagnose hypertension- induced renal microvascular dysfunction using renal diffusion magnetic resonance imaging (MRI) and to identify any correlation between blood pressure level and apparent diffusion coefficient (ADC) values. MATERIALS AND METHODS The study included 77 consecutive patients (41 women and 36 men). The patients were divided into 4 group...

This study aims to test the value of diffusion tensor (DT) magnetic resonance (MR) imaging and fractional anisotropy (FA) mapping in detection of early cord dysfunction due to cervical spondilotic myelopathy before myelopathy is apparent on T2 weighted MR images Methods Totally 21 patients with neurological signs and symptoms of degenerative cervical stenosis enrolled in the study. None of the ...

BACKGROUND AND PURPOSE Recent experimental data have shown that an increase of excitatory amino acids and the initiation of inflammatory responses within the injured spinal cord may play a role in post-traumatic syringomyelia. The purpose of this study was to determine whether diffusion-weighted MR imaging with apparent diffusion coefficient (ADC) maps could provide earlier evidence of spinal c...