INTRODUCTION Whipple's disease (WD) is a chronic, multisystemic infectious disease caused by Gram-positive bacillus Tropheryma whipplei (T.w.). Its common symptoms arise in the digestive system, however, during the infection the CNS (Central Nervous System) may also be affected. AIM The aim of this work is to present a case report of a patient diagnosed with Whipple's disease with dominant ne...

Menbutone is often used to stimulate the hepato-digestive activity in case of digestive disorders and hepatic insufficiency different species (cattle, sheep, goats, pigs, horses, dogs) because it has choleretic cholagogue effects increases gastric pancreatic juices. The objective was develop validate an HPLC method quantify menbutone sheep plasma using sparfloxacin as internal standard. mobile ...

Over the past decade, the emergence of microRNA (miRNA) research has firmly established this molecular family as a key component in cells. MiRNAs, which function as negative gene regulators, participate in multiple biological processes and maintain homeostasis in cells. The dysregulation of miRNA may contribute to numerous human disorders, including cancer. Recently, miR-196 was found to be abe...

From the Labor&ire de Biochimie, U.E.R. 58, Universit6 Paris VI Paris, France; the Service de Biochimie C,E.N. Saclay, 91190 Gif-sur-Yvette France; und the Reproduction Research Branch, National Institute oj Child Health and Human Developmeni and the Laboratory of Chemical Biology, National Institutes of Arthritis Metabolic, and Digestive Diseases, National Institutes of Health, Bethesda, Maryl...

Details about gastric physiology and pathophysiology are described. Other methods, some of them not used today, are also mentioned. Gastric emptying by radionuclides is important for checking normal function of the upper digestive system. The fried eggs etc. technique and not the liquid meal technique is preferred. In conclusion, gastric emptying by radionuclides, although other techniques have...

In 1898 Steinitz noted that the ingestion of raw egg-white by dogs was followed by vomiting and diarrhea. This interesting observation appears to have passed almost unnoticed, although no other native proteins are known to give rise to such digestive disorders. When these same facts were observed by Mendel and Lewis in 1913, their possible bearing on the wide spread use of raw eggs in various d...

Enteric neuropathy is emerging as a central theme in a range of digestive tract pathologies. Aberrant nitric oxide (NO) signaling by cellular components of the enteric nervous system or by inappropriate processing of dietary nitrite represents potential disease factors in delayed gastric emptying, diabetic gastroparesis, hypertrophic pyloric stenosis, and in inflammatory barrier dysfunction of ...

The enteric nervous system (ENS) controls and modulates various functions of the digestive tract such as motility, exocrine and endocrine secretion, local microcirculation, inflammation and neuroimmunity. This system is autonomous from the central nervous system (CNS), although they share many neurons and neurotransmitters. The CNS may exert a modulatory role on ENS through brainstem and subcor...

In 1898 Steinitz noted that the ingestion of raw egg-white by dogs was followed by vomiting and diarrhea. This interesting observation appears to have passed almost unnoticed, although no other native proteins are known to give rise to such digestive disorders. When these same facts were observed by Mendel and Lewis in 1913, their possible bearing on the wide spread use of raw eggs in various d...