نتایج جستجو برای: dimensional electrophoresis

تعداد نتایج: 443046  

Journal: :Proceedings of the National Academy of Sciences 2015

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010
Kazuya Nagano Sunao Imai Shinsaku Nakagawa Shin-ichi Tsunoda Yasuo Tsutsumi

Molecular biomarkers are keys to the development of new diagnostic protocols and therapies. Recently, significant research effort has been devoted to the development of these biomarkers using various approaches. Perhaps the most promising approach is disease proteomics. This method involves analyzing and identifying changes in the expression pattern at the protein level in the diseased conditio...

2017
Matthew P. Padula Iain J. Berry Matthew B. O′Rourke Benjamin B.A. Raymond Jerran Santos Steven P. Djordjevic

Methodologies for the global analysis of proteins in a sample, or proteome analysis, have been available since 1975 when Patrick O'Farrell published the first paper describing two-dimensional gel electrophoresis (2D-PAGE). This technique allowed the resolution of single protein isoforms, or proteoforms, into single 'spots' in a polyacrylamide gel, allowing the quantitation of changes in a prote...

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