Systematic transrectal ultrasound (TRUS)-guided biopsy is the standard method for a definitive diagnosis of prostate cancer. However, this biopsy approach uses two-dimensional (2D) ultrasound images to guide biopsy and can miss up to 30% of prostate cancers. We are developing a molecular image-directed, three-dimensional (3D) ultrasound image-guided biopsy system for improved detection of prost...

Couinaud segmentation is a widely used liver partitioning scheme for describing the spatial relation between diagnostically relevant anatomical and pathological features in the liver. In this paper, we propose a new methodology for effectively conveying these spatial relations during the ultrasound examinations. We visualize the two-dimensional ultrasound slice in the context of a three-dimensi...

We prospectively evaluated real-time ultrasound speckle tracking for monitoring soft tissue motion for image-guided radiotherapy. Two human volunteers and 1 patient with a proven hepatocellular carcinoma, who was being prepared for radiation therapy treatment, were scanned using a clinical ultrasound scanner modified to acquire and store radiofrequency signals. Scans were performed of the liver...

The diagnostic ultrasound was considered safe after the intensity threshold was known and the output intensity (Ispta) was regulated to be less than 10 mW/cm2 in diagnostic devices in Japan, and diagnostic ultrasound was thought safe in USA when both thermal index (TI) and mechanical index were less than 1.0 in the obstetrical setting. Simple B-mode machine was not concerned from the thermal re...

We examined 49 coronary stents in 33 patients after angiographically guided optimization of the deployment by intracoronary ultrasound, and compared the findings of a conventional 2-dimensional analysis approach with the results obtained from an automatic lumen recognition provided by a 3-dimensional reconstruction system. The automatic lumen analysis demonstrated that only 15 stents (31%) fulf...

This paper describes a learning environment for image-guided prostate biopsies for cancer diagnosis; it is based on an ultrasound probe simulator virtually exploring real datasets obtained from patients. The aim is to make the training of young physicians easier and faster with a tool that combines lectures, biopsy simulations and recommended exercises to master this medical gesture. It is desi...

A method for the controlled positioning of small particles in one or two dimensions by an ultrasound field excited by a surface wave is presented. Particles of a diameter between 10 and 100 microm placed on a surface can be concentrated at certain locations and moved over the surface. In other approaches it is possible to let the particle levitate freely in the fluid. However for the use of ult...

Facial clefts are among the most common congenital anomalies, with a point prevalence of approximately 1:500 to 1:1000 live births.1,2 Prenatal detection and diagnosis has been recognised as useful to facilitate prenatal counselling, to evaluate genetic risks, and to prepare the parents psychologically to accept and plan for neonatal surgery after birth. To improve the evaluation of these defec...

We report new results on acousto-optical tomography in phantom tissues using a frequency chirp modulation and a CCD camera. This technique allows quick recording of three-dimensional images of the optical contrast with a two-dimensional scan of the ultrasound source in a plane perpendicular to the ultrasonic path. The entire optical contrast along the ultrasonic path is concurrently obtained fr...